Cancer research
The CAR T-cell therapy for acute lymphoblastic leukemia market is currently in the growth stage of its lifecycle, driven by the success of pioneering therapies such as Kymriah and the increasing demand for innovative treatments. The market is expected to grow at a significant rate due to advancements in diagnostic
Cancer research
A new study conducted by researchers from Fourth Hospital of Hebei Medical University has evaluated the cost-effectiveness of adoptive cellular immunotherapy (ACI) combined with chemotherapy versus chemotherapy alone in Chinese patients with metastatic colorectal cancer (mCRC). The study, published in Frontiers in Oncology, found that ACI combined with chemotherapy provided
Cancer research
Recent research by Oxford University and Cancer Research UK suggests that consuming an additional glass of milk a day could significantly reduce the risk of bowel cancer. The study found that drinking an extra 244g of milk, roughly one large glass, lowered the risk of developing bowel cancer by 17%
Cancer research
Research from the Fox Chase Cancer Center has shown that biweekly dosing of trifluridine-tipiracil (TAS-102) can reduce the rates of myelosuppression in patients with metastatic colorectal cancer while maintaining efficacy. This alternative dosing schedule may potentially broaden the utilization of TAS-102 in patients with borderline performance status and provide a
Cancer research
Shenzhen University researchers have published new study results on disease progression, revealing that pericytes play a crucial role in facilitating metastatic dissemination and modulating immune response in malignancies such as castration-resistant prostate cancer (CRPC). The investigation leveraged single-cell transcriptomics and immunofluorescence staining to ascertain the presence and spatial distribution of
Cancer research
Research from the University of Notre Dame highlights the importance of dietary interventions in enhancing immunotherapy responses in prostate cancer. Investigators found that certain diets, such as the ketogenic diet, and bioactive compounds like white button mushroom extract, can modulate the tumor microenvironment and improve immunotherapy efficacy. Additionally, specific diet-derived
Cancer research
Researchers at Medical University of Warsaw have made significant progress in understanding cancer gene therapy, particularly in the treatment of glioblastoma, the most aggressive and common type of primary brain cancer. Current treatments result in only a 12- to 15-month mean overall survival, emphasizing the urgent need for more effective
Cancer research
A team of researchers from Oregon State University has made a significant discovery in the field of gene therapy. By incorporating 40 saponins into a model lipid nanoparticle (LNP) formulation, they found that certain saponins, such as quillaic acid and macranthoidin B, can increase the LNP transfection efficiency and endosomal
Cancer research
Research conducted at Shandong University in the People's Republic of China has led to the development of a predictive model capable of identifying patients with metastatic colorectal cancer (mCRC) who may benefit from primary tumor resection (PTR). The study utilized clinical data from the Surveillance, Epidemiology, and End
Cancer research
Investigators at Sun Yat-Sen University in Guangzhou, People's Republic of China, have found that Continuous Glucose Monitoring (CGM) significantly improves outcomes in type 2 diabetes patients undergoing colorectal cancer surgery. The study, published in Frontiers in Medicine, demonstrated that CGM reduces glycemic variability, surgical complications, and promotes wound
Cancer research
Researchers from Peking University have revealed significant disparities in lung cancer care under tiered social health insurance (SHI) in China. A population-based study of 319,677 patients diagnosed with lung cancer between 2017 and 2021 in Shandong, China, found that those under the Urban Employee Basic Medical Insurance (UEBMI) scheme
Cancer research
Research from Tarbiat Modares University in Tehran, Iran, has made significant progress in cancer gene therapy, particularly in the development of bisphosphonate-based drug delivery systems. These systems target bone-mineral matrices, inhibiting excessive osteoclast activity associated with various bone disorders. The study highlights the potential of these systems in concentrating therapeutic
