Cancer research
Researchers at the Universidad de Las Americas have conducted a comprehensive review on the role of oncogenic viruses in modulating the epigenetic landscape of human cancer. The study highlights the significant contribution of viruses, such as human papillomavirus (HPV), Epstein-Barr virus (EBV), hepatitis B virus (HBV), and hepatitis C virus
Cancer research
Researchers from the Uniformed Services University of the Health Sciences have made a breakthrough discovery in the field of acute myeloid leukemia (AML) by identifying a five-gene signature that can predict both event-free survival (EFS) and overall survival (OS) in patients with AML. This significant finding has the potential to
Cancer research
Researchers from the National Cancer Institute (NCI) have made a groundbreaking discovery in the field of lung cancer, highlighting the connection between inflammatory diseases and the risk of lung cancer in individuals who have never smoked. According to a study published in Nature Communications, conditions such as Chronic Obstructive Pulmonary
Cancer research
Researchers from Central South University have conducted a comprehensive investigation to elucidate the biological mechanisms linking HIV infection to lung cancer development. By integrating genetic datasets and developing predictive models, the study aimed to provide valuable insights for developing targeted prevention and treatment strategies for HIV-positive populations. The investigation characterized
Cancer research
Leap Therapeutics, a biotechnology company focused on developing targeted and immuno-oncology therapeutics, reported updated results from the DeFianCe study, a Phase 2 study of sirexatamab (DKN-01), an anti-DKK1 monoclonal antibody, in combination with bevacizumab and chemotherapy, in patients with advanced microsatellite stable (MSS) colorectal cancer (CRC) who have received one
Cancer research
Research has confirmed that taking an aspirin a day can significantly reduce the risk of bowel cancer in individuals with Lynch syndrome, a rare genetic condition. A new trial involving 1,900 participants, including 1,879 people with Lynch syndrome from the UK, Europe, and Australia, suggests that a low
Cancer research
A disturbing trend of rising rates of early-onset bowel cancer is affecting people aged 25-49, with women being particularly impacted. According to a major paper published in The Lancet Oncology, this global phenomenon is seen in 27 out of 50 countries and territories studied. In England, the rate of early-onset
Cancer research
GlycoNex, Inc., a clinical-stage biotechnology company, has announced promising preclinical results for its first-in-class antibody-drug conjugate (ADC), GNX1021, in treating gastric cancer. The company's innovative approach may offer a novel treatment option for patients who are ineligible for existing therapies. With a strong safety profile comparable to that
Cancer research
Researchers at the Mayo Clinic Comprehensive Cancer Center have made a groundbreaking discovery in the treatment of colon cancer. In a study presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, the team found that adding immunotherapy to chemotherapy after surgery for patients with stage 3 (node-positive)
Cancer research
Researchers at the University of Texas MD Anderson Cancer Center have identified key intraoperative ultrasound (iUS) findings that correlate with adequate decompression and prognostication of functional status in patients undergoing separation surgery for high-grade malignant epidural spinal cord compression. The study, published in Neurosurgical Focus, analyzed 24 iUS images and
Cancer research
Researchers from Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine have discovered that when cancer spreads to new sites throughout the body, it undergoes changes that increase its genetic complexity. This study provides fresh insights into the evolution of cancers during metastasis, which could aid in developing more
Cancer research
Research conducted at Tohoku University Hospital in Sendai, Japan, has highlighted concerns about the risk of radiation-induced malignant brain tumors in pediatric patients with acute lymphoblastic leukemia (ALL). According to the study, two patients developed secondary glioblastoma, a rare and aggressive type of brain cancer, after undergoing radiation therapy for
