Cancer research
A new study has highlighted the importance of Federally Qualified Health Centers (FQHCs) in addressing smoking and lung cancer screening in the United States. Researchers from the University of Colorado conducted a pilot study to assess the feasibility, acceptability, and appropriateness of a method for selecting implementation strategies to address
Cancer
Researchers at Genentech Inc. have successfully engineered interleukin-18 (IL-18), a pro-inflammatory cytokine, to enhance its stability, half-life, and manufacturability, potentially paving the way for its use in cancer immunotherapy. The engineered variant, disulfide-stabilized IL-18 Fc-fusion (dsIL-18-Fc), demonstrated improved stability and mammalian host cell production yields compared to the wild-type cytokine.
Cancer
Researchers from the University of Chicago have developed a new platform for cancer immunotherapy using chimeric antigen receptor (CAR) T cell therapy. This innovative approach has shown promise in treating hematological cancer, while addressing challenges such as antigen loss, toxicity, and complex manufacturing. The new platform, known as the CAR-fragment
Cancer research
A new research study has shed light on the effectiveness of avelumab first-line maintenance in patients with advanced urothelial carcinoma (UC). The study, led by researchers at the University of Washington, has provided insights into the real-world outcomes of this treatment approach, which has been approved for patients who are
Cancer research
A team of researchers from Nanjing University has shed new light on the role of fungi in cancer initiation and progression, particularly in acral melanoma (AM). The study, published in the Journal for ImmunoTherapy of Cancer, found that intratumoral fungi have distinct characteristics in AM tumors compared to adjacent non-tumor
Cancer
Researchers at Tarbiat Modares University in Iran have made a significant discovery in the field of cancer treatment. The team, led by Shokouh Rezaei, has developed folate-functionalized zein-PEI nanoparticles that show enhanced biocompatibility and targetability. These nanoparticles have been designed to deliver targeted cancer therapy with improved stability and reduced
Cancer research
A recent study published in Ethnicity & Health has shed light on the alarming racial disparities in the treatment and mortality rates of prostate cancer patients. Researchers analyzed a cohort of 244,468 men aged 65 and older, diagnosed with prostate cancer between 2007 and 2015. The findings revealed significant
Cancer research
Research has identified a new potential treatment for lung cancer, with gene therapy showing promising results in targeting cancer cells while sparing healthy ones. According to a study published in the Advanced NanoBiomed Research journal, researchers have created a gene therapy delivery system using chemically functionalized nanoscale graphene oxide (GO)
Cancer treatment
Researchers at Nantong University in China have made significant progress in developing tumor mRNA vaccines, a personalized medicine approach to cancer treatment. According to a report, the mRNA vaccine has shown great potential in treating various tumors due to its unique advantages and advantages. However, challenges remain in the complexity
Cancer
Researchers at the University of California San Diego have made a groundbreaking discovery in the field of cancer immunotherapy. A virus that typically infects black-eyed peas, known as the cowpea mosaic virus (CPMV), has shown great promise in attacking cancer cells. In a study published in Cell Biomaterials, a team
Cancer research
Researchers at the University of Michigan and Oregon Health & Science University have identified a gene program associated with extreme non-response to a common prostate cancer drug, enzalutamide. The study, led by Joshi Alumkal and Zheng Xia, sheds light on why some tumors are treatment-resistant and explores potential new treatment
Cancer
Research published in the Journal of Sleep Research has found a strong association between sleep disturbances and suicidality in depressed individuals. According to the study, conducted by the Institute for Cancer Research and Treatment (IRCCS) San Raffaele Scientific Institute in Milan, Italy, polysomnographic features of depressed suicidal and non-suicidal subjects
