Cancer treatment

Cancer research

KAHR Announces Positive Results for DSP107 in Combination with Atezolizumab in Metastatic Colorectal Cancer Patients

KAHR, a clinical-stage biotech company, announced positive results for the Phase 2 dose expansion cohort of DSP107, a first-in-class bi-specific 4-1BB T-cell engager, in combination with atezolizumab, an anti-PD-L1 cancer immunotherapy, in patients with 3rd line microsatellite stable metastatic colorectal cancer (MSS-CRC). The combination demonstrated anti-tumor activity and extended survival,

Cancer

Breakthrough in Cancer Immunotherapy: Magnetic Nanoparticles Boost T-Cell Response

Researchers from Ural State Medical University have made a significant breakthrough in cancer immunotherapy using magnetic nanoparticles. According to their study, the use of monocyte-derived dendritic cells (moDCs) sensitized by cancer-associated antigens and loaded with magnetic nanoparticles (MNPs) enhances the T-cell mediated anti-tumor immune response. This innovative approach has the

Cancer research

Medicus Pharma Receives Regulatory Approval for Phase 2 Trial of Non-Invasive BCC Treatment

Medicus Pharma has secured regulatory clearance from the UAE Department of Health to conduct a Phase 2 clinical trial evaluating its D-MNA therapy for basal cell carcinoma (BCC) of the skin. The trial, SKNJCT-004, will involve 36 patients across four medical centers in the UAE and compare the efficacy of

Cancer research

Unveiling the Potency of ZnO and CuO Nanocomposites in Combating Hepatocellular Carcinoma

Scientists at the National Research Centre have conducted a groundbreaking study on the effectiveness of zinc oxide and copper oxide nanocomposites in treating liver cancer. The research, recently published in Scientific Reports, found that a specific combination of these nanocomposites, denoted as N1, exhibited exceptional cytotoxic activity against hepatocellular carcinoma

Cancer research

Breakthrough in Cancer Detection: Nanoparticle-Based Biosensor Enables Early Diagnosis

A team of researchers at the University of New South Wales has made a significant breakthrough in the field of cancer detection, using a nanoparticle-based 'dispersible electrodes' biosensor to detect ultra-low concentrations of microRNA-155 (miRNA-155) from a single breast cancer spheroid. This innovative approach enables early diagnosis and

Cancer

City of Hope Researchers Present Groundbreaking Cancer Treatment Approaches and Combinations at ASCO Annual Meeting

At the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, researchers from City of Hope are set to present novel cancer treatment approaches and combinations that could reduce cancer risk and improve survival. These breakthroughs include innovative combination therapies that target and shrink tumors once untouchable, identifying cancer biomarkers

Cancer

Nivolumab Therapy Linked to Cardiotoxicity

Researchers from the Department of Medicine, Lahore, Pakistan have conducted a review of the current literature on cardiotoxicity associated with nivolumab therapy. Nivolumab, a monoclonal antibody targeting the programmed cell death receptor 1 (PD-1) receptor, has been approved by the FDA for various cancers, including advanced melanoma, metastatic renal cell

Cancer research

Researchers Identify Prognostic Model for Liver Cancer Using Single-Cell Sequencing and Bulk RNA Sequencing

Research investigators at the Fifth Affiliated Hospital of Guangzhou Medical University have made a groundbreaking discovery in the fight against liver cancer. By combining single-cell sequencing and bulk RNA sequencing, they have identified a prognostic model that can accurately predict the prognosis of hepatocellular carcinoma (HCC) patients and their response

Cancer

Childhood Cancer Survivors Face Late-Onset Pulmonary Complications

Childhood cancer survivors often develop late-onset pulmonary complications, with some experiencing severe respiratory issues, including interstitial lung disease, pulmonary fibrosis, and bronchiolitis obliterans. A recent study conducted by researchers from the Children's Hospital of Philadelphia has shed light on the genetic susceptibility markers that contribute to these complications.

Cancer research

Combining Cetuximab and Immunotherapy for Treating MSS/pMMR Colorectal Cancer

Colon cancer remains a formidable global health challenge, with the majority of patients exhibiting microsatellite stable (MSS) and proficient mismatch repair (pMMR) tumors that are largely unresponsive to immune checkpoint inhibitors (ICIs). Researchers from Hubei Key Laboratory of Tumor Biological Behaviors have discussed new findings in colon cancer, highlighting the

Cancer

Tannic Acid-Based Nanoplatforms Show Promise for Cancer Treatment

Researchers at Wuxi University have made a breakthrough in the development of a novel nanoparticle system, tannic acid-condensed lipid nanoparticles (TLNPs), which has shown significant potential in targeting and treating breast cancer. The TLNPs exhibited excellent stability, sustained drug release properties, and efficient cellular uptake, making them a promising approach

Cancer

Biomimetic Metal-Organic Frameworks in Cancer Theranostics: A Promising Approach

Researchers from the Manipal Academy of Higher Education have made significant discoveries in the field of cancer theranostics by exploring biomimetic metal-organic frameworks (MOFs). According to a recent study published in Nanoscale, MOFs have shown promising features such as adjustable porosity, improved surface area, and multifunctionality, but are limited by