Cancer treatment
Nanoparticles may hold the key to effective treatment of cancer by targeting the VEGF/VEGFR pathway, which plays a crucial role in regulating angiogenesis, the formation of new blood vessels. Researchers at the Poznan University of Medical Sciences have conducted a comprehensive review of nanoparticles designed for selective targeting of
Cancer
Researchers at the Icon Cancer Foundation have initiated a clinical trial to evaluate the feasibility of response-adapted or response-and-anatomical-adapted Stereotactic Ablative Body Radiotherapy (SABR) in patients with advanced melanoma receiving immunotherapy. The trial, registered with the Australian New Zealand Clinical Trials Registry (ANZCTR) as ACTRN12624001299594, aims to develop a method
Boston University
Boston University doctoral students Joshua McGee and Jack Kirsch were running experiments to see if RNA sequences with small changes in nucleotides could still work. After dozens of attempts, they unexpectedly stumbled upon a breakthrough: a modified self-amplifying RNA (saRNA) that replicates itself in a cell to produce a higher
Boston University
Boston University researchers Joshua McGee, Jack Kirsch, Mark Grinstaff, Wilson Wong, and Florian Douam have made a groundbreaking discovery in COVID vaccine development, creating a new and improved self-amplifying RNA (saRNA) vaccine. Through a year-long research project, the team successfully tested their modified saRNA vaccine in mice, finding that it
Cancer treatment
The latest report from Novotech, a global full-service clinical Contract Research Organization, highlights the transformative potential of RNA therapies in modern medicine. With their highly-targeted mechanisms and versatility, RNA-based treatments have transitioned from a novel concept to a promising frontier in disease treatment. The report details the current landscape, advancements,
Biological products industry
CancerVax, Inc. has filed a new patent application for a revolutionary universal cancer treatment platform that leverages the body's immune system to fight cancer. The platform uses Smart mRNA technology to detect, mark, and kill only cancer cells, reducing the toxic side effects associated with traditional cancer treatments.
Cancer research
A new article published in Frontiers in Immunology reviews the significant role of tumor vaccines in basic research and clinical treatment, and explores the use of artificial intelligence (AI) technology to screen novel adjuvants from databases. With the COVID-19 pandemic highlighting the importance of vaccines, researchers are working to enhance
Cancer research
A recent study conducted by scientists at the University of Milan has shed light on the potential benefits of fasting-mimicking diet (FMD) in complementing the effects of cancer treatment. The study found that this dietary pattern, which mimics the effects of fasting on the body while allowing for calculated food
Cancer treatment
Fresh data from a trial evaluating the use of 5-alpha reductase inhibitors as an alternative to LHRH-agonists in treating prostate cancer has shown promising results. According to the research from the University of Chicago, men treated with 5-ARIs had better preservation of hormonal quality of life with no obvious detriment
Cancer diagnosis
As a resilient cancer survivor, Meg Wilkinson has turned her life-threatening experience into a mission to understand the omentum, a vital yet understudied organ that plays a crucial role in cancer treatment and overall health. Her journey began in 2014 when she was diagnosed with ovarian cancer, a disease notoriously
Cancer
A new study published in the journal Cancers has made a significant breakthrough in personalized medicine, identifying mutations in * * FBXW7* * and * * SMAD4* * as predictors of clinical outcome in metastatic colorectal cancer. The research, conducted by a team of scientists from the University of Barcelona, used next-generation sequencing (NGS) to analyze
Cancer
Researchers at the Indian Institute of Science Education and Research have made a significant discovery in the field of biotechnology, specifically in cancer gene therapy. By understanding the sulfation pattern of glycosaminoglycans (GAGs), such as heparan sulfate (HS) and chondroitin sulfate (CS), scientists have developed a potential drug- or gene-delivery
