Cancer research
Researchers at the University of California San Diego School of Medicine have developed a new approach to targeting aggressive, treatment-resistant cancers by optimizing an anti-avb3 antibody that activates macrophages, a type of immune cell already abundant in advanced avb3+ tumors. This innovative therapy has shown promising results in both patient
Cancer research
An international study has revealed that age-based classifications in the treatment of acute myeloid leukemia (AML) may be overly simplistic and no longer reliable. Researchers from the Alliance for Clinical Trials in Oncology and the Acute Myeloid Leukemia Cooperative Group analyzed data from 2,823 adult AML patients treated in
Apoptosis
Researchers at Alfred Health in Melbourne, Victoria, Australia, have made a significant discovery in the field of melanoma treatment. A study published in the Journal for ImmunoTherapy of Cancer reveals that the expansion of a specific type of immune cell, known as Ki67-positive effector T-cells, after just one cycle of
Cancer
A groundbreaking study involving the Exact Sciences' Falcon Registry Real-World Evidence (RWE) program is enrolling over 1,000 patients to test the effectiveness of a simple blood draw in detecting over 50 types and subtypes of cancer, including those without routine screening guidelines. The Cancerguard MCED test uses DNA
Cancer research
Fresh data on Oncology - Acute Myeloid Leukemia have been presented in a new report. According to research from the University of Texas MD Anderson Cancer Center, Donor-Derived Vg9Vd2 T cells are a promising candidate for treating patients with acute myeloid leukemia (AML) who are unfit for intensive chemotherapy. The
Cancer
Researchers at the Institute of Biomedical Sciences have discovered a novel approach to cancer immunotherapy using dendritic cell-targeted liposomes. The study, published in the Journal of Nanobiotechnology, reveals that inhibiting the aryl hydrocarbon receptor (AhR) in dendritic cells enhances the production of IL-12 and IFN-g, promoting tumor-killing activity. This breakthrough
Cancer
Researchers from University Sains Malaysia have recently published a review in the European Journal of Pharmacology highlighting the potential of RNA sequencing in the translational repurposing of antimicrobials, disulfiram, and metformin for cancer therapy. According to the study, metformin has shown promising anticancer activity through the induction of multiple regulated
Cancer research
Researchers from Kashan University of Medical Sciences in Iran have made significant progress in understanding the role of probiotics and microbiome-derived metabolites in cancer therapy. The study, published in the journal Current Research in Biotechnology, highlights the potential of probiotics in shaping the landscape of cancer prevention and treatment. The
Cancer research
Researchers at the National Institute of Pharmaceutical Education and Research (NIPER) have made a significant discovery in the field of cancer gene therapy. According to a new report published in Biomaterials Advances, a novel nano-carrier system has been developed that combines darolutamide and hesperetin to effectively manage prostate cancer. The
Cancer research
Researchers from the Nanjing University of Chinese Medicine have developed a novel therapeutic platform for treating bladder cancer, utilizing a synergistic combination of cerium oxide nanostructures and gold nanoparticles loaded with astragaloside IV. The core-shell structured nanocomposites demonstrated remarkable pro-apoptotic effects, inducing a 5.11-fold increase in apoptosis induction compared
Cancer
Researchers at the University of Chicago have made a significant advancement in cancer treatment by developing a new nanoscale metal-organic framework (nMOF) that enhances the efficacy of radiotherapy while minimizing normal tissue toxicity. The study, published in the journal Chemistry of Materials, introduces a hafnium-based nMOF (Hf-Pc) that exhibits enhanced
Cancer
Scientists at Guangzhou Red Cross Hospital have made a significant discovery in the field of cancer gene therapy, developing a novel nanoprobe for colon cancer treatment. The researchers created a lipophilic NIR-II-fluorescence membrane probe (BMP1-2) that can effectively label lipid-bilayer structured nanovectors (LBSNs) composed of immunogenic probiotic outer membrane vesicles
