Cancer research
Researchers at the University of Alabama have found that genetically modified mesenchymal stem cells (MSCs) expressing interferon-beta can effectively reduce tumor volume and promote apoptosis in mice with prostate cancer lung metastasis. This study represents a promising new approach in the fight against cancer, leveraging the ability of MSCs to
Cancer research
Researchers in Berlin, Germany have completed a prospective randomized phase III trial investigating the efficiency of active specific immunotherapy (ASI) in preventing recurrent colorectal cancer. The study involved 51 patients with histologically confirmed liver metastases from colorectal cancer who were randomized to receive either the vaccination or control group. After
Cancer
Combination therapy targeting vascular endothelial growth factor-C (VEGF-C) and VEGF-A has shown promising results in inhibiting cancer metastasis in a murine metastatic mammary cancer model. Scientists from Osaka Medical College observed that direct intratumoral injection of plasmid siRNA vectors targeting VEGF-C and/or VEGF-A resulted in significantly reduced tumor volume,
Cancer
A study published in Cancer Gene Therapy has revealed the potential of Newcastle disease virus (NDV) as a treatment for various cancers, including lung cancer. The study, conducted by researchers at the Hebrew University in Jerusalem, Israel, demonstrated that an attenuated lentogenic isolate of NDV (HUJ) selectively killed human and
Cancer treatment
Scientists in the United States have reported new findings in the field of cancer research, revealing that nonspecific immunotherapy using intratumoral lipopolysaccharide and zymosan A, but not GM-CSF, is effective in generating an anti-tumor response in subcutaneous RG-2 gliomas. This treatment approach may be useful in generating an anti-tumor response
Cancer treatment
Scientists at the M.D. Anderson Cancer Center have successfully combined targeted therapy with radiation treatment to enhance the therapeutic efficacy of lung cancer treatment. Researchers evaluated the feasibility of using ZD6474, a small-molecule inhibitor of VEGFR2 and EGFR tyrosine kinases, in conjunction with radiation therapy in an orthotopic model
Cancer treatment
Researchers from Kyushu University in Japan have made significant contributions to cancer immunotherapy and diagnostics through three distinct studies published in international journals. These findings have the potential to revolutionize the treatment and management of various cancers. Key Takeaways: * A new method using recombinant Sendai virus (rSeV) has been developed
Cancer treatment
University of California, U.S. researchers have published several studies that challenge existing knowledge in cancer research. A team of investigators at University of California, U.S. has found that genetic association studies using case-control designs are susceptible to false-positive and false-negative results if there are differences in genetic ancestry
Pharmaceutical industry
Pro-Pharmaceuticals, Inc. has signed an agreement with CESAR, the Central European Society for Anticancer Drug Research, to recruit biliary cancer patients in Germany for its Phase II clinical trial. The trial, which is evaluating the safety and efficacy of DAVANAT in combination with 5-FU for the treatment of advanced biliary
Pharmaceutical industry
EntreMed, Inc. has made significant announcements regarding its advancements in cancer and inflammation treatments. The company has commenced a multicenter study on its drug candidate, MKC-1, in non-small cell lung cancer (NSCLC) patients. Additionally, EntreMed has established a scientific advisory board to advise on its priority research and drug development
Drugs
Researchers at Sahlgrenska University, Sweden have made significant discoveries in the fields of immunology, cardiology, and oncology, shedding light on new treatment options and mechanisms for various diseases. These breakthroughs highlight the ongoing efforts of the university to push the boundaries of medical research and advance the field of healthcare.
Drugs
Researchers at the University of Texas, M.D. Anderson Cancer Center, have made significant progress in understanding and treating various forms of cancer. According to recent studies, a tyrosine kinase inhibitor has shown promise in reducing lymph node metastasis in colon cancer, while early identification and treatment of cancer-treatment-induced bone
