Cancer
A new study has shed light on the key mechanisms driving gastric cancer progression, immune evasion, and treatment resistance. According to the research, glucose metabolism reprogramming plays a pivotal role in promoting tumor progression, immune evasion, and treatment resistance in gastric cancer. The study, conducted by a team of researchers
Cancer
Scientists at Guangzhou Red Cross Hospital have made a significant discovery in the field of cancer gene therapy, developing a novel nanoprobe for colon cancer treatment. The researchers created a lipophilic NIR-II-fluorescence membrane probe (BMP1-2) that can effectively label lipid-bilayer structured nanovectors (LBSNs) composed of immunogenic probiotic outer membrane vesicles
Cancer
Sunshine Biopharma Inc.'s wholly owned subsidiary, Nora Pharma Inc., has achieved a significant milestone with the approval from Health Canada for the commercialization of Domperidone, a prescription medication used to relieve nausea and vomiting. This approval marks a strategic expansion into the generic pharmaceuticals market for Sunshine Biopharma,
Cancer
Researchers at the Institute of Biomedical Sciences have discovered a novel approach to cancer immunotherapy using dendritic cell-targeted liposomes. The study, published in the Journal of Nanobiotechnology, reveals that inhibiting the aryl hydrocarbon receptor (AhR) in dendritic cells enhances the production of IL-12 and IFN-g, promoting tumor-killing activity. This breakthrough
Cancer
The 27th annual Angel Ball GALA was held on Monday, October 27th at Cipriani Wall Street in New York City, bringing together a star-studded crowd to raise money for cancer research. This year's event honored outstanding individuals who have made significant humanitarian and philanthropic contributions to cancer research,
Cancer
Investigators at Jiangsu Normal University in Jiangsu, People's Republic of China, have identified a novel "contextual programmed lethality" mechanism targeting the lactylation-ferroptosis axis in gastric cancer, highlighting the potential of the flavonoid breviscapine as a therapeutic strategy against diabetes-aggravated cancers. The research demonstrates that breviscapine inhibits
Cancer
Mollie Cowell-Walker, a local performer and burlesque instructor, is set to dazzle the festive season with her Christmas show in Fleetwood. As the Burlesque Chair Dance Semi-Final Winner of the North, Cowell-Walker aims to empower women through dance fitness, promoting body confidence and self-love. The Fleetwood Christmas Burlesque Show promises
Cancer
Severe obesity is a growing health concern in the United States, affecting millions of adults. A recent cross-sectional study published in JAMA Network Open reveals that individuals with a body mass index (BMI) of 50 or higher have significantly lower cancer screening rates. This alarming trend highlights the need to
Cancer
Researchers at the University of Chicago have made a significant advancement in cancer treatment by developing a new nanoscale metal-organic framework (nMOF) that enhances the efficacy of radiotherapy while minimizing normal tissue toxicity. The study, published in the journal Chemistry of Materials, introduces a hafnium-based nMOF (Hf-Pc) that exhibits enhanced
Cancer
Researchers from the Department of Gastroenterology, Successful Hospital Affiliated to Xiamen University in Fujian, People's Republic of China, have made significant breakthroughs in understanding the molecular mechanisms underlying gastric cancer (GC). By integrating transcriptomics and machine learning, the team identified several ferroptosis-related genes, including Glutamic-Oxaloacetic Transaminase 1 (GOT1)
Cancer
A new study has shed light on the potential impact of commonly used drugs, such as proton pump inhibitors, statins, and metformin, on gastric cancer morbidity in Ukraine. Researchers found that the consumption of these medications, as well as cysteine derivatives, increased by 98.61% between 2014 and 2020. Despite
Cancer
Research from Huazhong Agricultural University has published a comprehensive database, cfMethDB, dedicated to circulating cell-free DNA (cfDNA) methylation in cancer. The database integrates 4828 publicly available datasets and identifies 1,048,770 differentially methylated cytosines (DMCs) as candidate biomarkers across seven cancer types. This breakthrough has the potential to significantly
