Youth
Dr. Kara Kelly, Chair of Pediatrics at Roswell Park Comprehensive Cancer Center, has been recognized for her efforts to advance care for young people with blood cancers. She has been honored with awards and new leadership positions by several national and international oncology organizations. Dr. Kelly has dedicated countless hours
Cancer
Dr. Nicholas Reiter, an assistant professor of chemistry at Marquette University, has been awarded $1.68 million in R01 funding from the National Institutes of Health's National Institute of General Medical Sciences to investigate the misregulation of RNA binding proteins that lead to degenerative disorders and cancer. Reiter&
Cancer
Researchers at the University of Texas MD Anderson Cancer Center have made a significant discovery in cancer treatment, identifying predictive biomarkers for severe immune-related adverse events (irAEs) that can occur when patients receive immunotherapy. The study, published in the Journal for ImmunoTherapy of Cancer, used a novel method for long-amplicon
Cancer
Researchers from Sichuan University have published a new study on cancer gene therapy, focusing on the use of chimeric antigen receptor (CAR) engineered natural killer (NK) cells. The study highlights the potent capacity of NK cells to kill cancer cells while maintaining good tolerance for healthy cells. The researchers explore
Cancer
Researchers from the National Cancer Center Hospital in Tokyo, Japan, have launched a multi-institutional prospective observational study to investigate the utility of circulating tumor DNA (ctDNA) in detecting minimal residual disease (MRD) in patients with locally recurrent rectal cancer. The study aims to identify reliable prognostic and predictive biomarkers to
Cancer
Research published in Clinical Lung Cancer suggests that the combination of ramucirumab plus erlotinib (RAM + ERL) exhibits benefit compared with placebo plus erlotinib (PBO + ERL) in patients with untreated, metastatic, EGFR-mutated non-small-cell lung cancer (EGFR+ NSCLC). This study, known as RELAY, investigated the relationship between TP53 status and clinical outcomes
Cancer
A 54-year-old female patient diagnosed with diffuse large B-cell lymphoma developed interstitial pneumonia after undergoing standard treatment. The case study, published in the journal Cancer Pathogenesis and Therapy, highlights the potential risks and treatments associated with cancer gene therapy. Researchers from the Second Medical Center are investigating new approaches to
Cancer
Researchers at the University of Alabama at Birmingham have made significant progress in understanding the mechanisms of cancer gene therapy for glioblastoma, a highly malignant primary brain tumor. Despite standard therapies, glioblastoma's recurrence is virtually inevitable, leading researchers to explore emerging therapies, such as immunotherapy. A recent review
Cancer
Researchers have explored the conceptual framework of pragmatism in clinical trials using the American Society of Clinical Oncology's Targeted Agent and Profiling Utilization Registry Study (TAPUR) as a model. This study aims to identify signals of drug activity when FDA-approved drugs are matched to pre-specified genomic targets in
Cancer
A new study has highlighted the urgent need for a cost-effective and highly accurate method for early detection of gastric cancer, a malignancy with a low 5-year survival rate despite its high incidence. Current methods such as gastrointestinal X-ray and upper endoscopy are invasive, expensive, and expose patients to radiation,
Cancer
Researchers at the First Affiliated Hospital of Nanchang University in Nanchang, People's Republic of China, have discovered a novel gene signature based on RNA-binding protein (RBP) gene pairs to predict the prognosis of gastric cancer patients. This breakthrough finding has significant implications for cancer gene therapy and may
Cancer
Rep. August Pfluger has reintroduced the Aviator Cancers Examination Study (ACES) Act, which aims to study cancer incidence and mortality rates among aviators and aircrew who served in the Navy, Air Force, and Marine Corps. The bill, co-led by Rep. Jimmy Panetta, seeks to advance research on any correlation between
