Cancer
Recent research conducted at Chengdu Medical College in Sichuan, People's Republic of China, has shed light on the pivotal epigenetic driver of gastric cancer (GC) pathogenesis. The study, published in Cell Biology and Toxicology, highlights the role of N-6-methyladenosine (m(6)A) modification, orchestrated by methyltransferase-like 3 (METTL3)
Cancer
Researchers at the University of British Columbia have made significant progress in the field of cancer treatment, revealing that nearly half of humanity will develop cancer in their lifetime. Current therapies, particularly chemotherapeutic drugs, face significant challenges due to the lack of tissue-specific delivery. To address this issue, lipid-based nanoparticles
Cancer
Recent research at the First Hospital of Hunan University of Chinese Medicine has shed new light on the potential of metal nanoparticles in cancer diagnosis and treatment. The study, published in the journal Drug Delivery, revealed that metal nanoparticles (MNPs) have unique physicochemical properties that enable precise drug delivery and
Cancer
Research from the SRM Institute of Science and Technology has highlighted the potential of epigenetic therapies in cancer treatment. According to the study, epigenetic changes, such as DNA methylation and histone modifications, play a key role in cancer development and progression. These changes can be reversed, making them attractive targets
Cancer
Researchers at Sichuan Cancer Hospital have developed covalent organic frameworks (COFs) that can be tailored for use in cancer treatment and drug delivery. COFs are crystalline and porous materials formed from organic molecules that can have their mechanical properties adjusted to suit various applications. This review summarizes the strategies for
Cancer
Researchers at Guangzhou University of Chinese Medicine have made a significant discovery in the field of cancer immunotherapy. A new customized immunomodulator, developed by the team, has been shown to comprehensively reinforce the anti-tumor immunological cascade. This breakthrough has the potential to enhance the efficacy of immunotherapy for cold tumors,
Cancer
Researchers have discovered that tumor necrosis factor (TNF) plays a critical role in the development of colorectal cancer (CRC) through cellular reprogramming in intestinal epithelial cells. According to a new report published in Cell Communication and Signaling, prolonged TNF exposure can trigger CRC progression by inducing the expression of doublecortin-like
Cancer
Research published in the journal Clinical Genitourinary Cancer has highlighted the increasing incidence of early-stage kidney cancer, leading to a focus on comparative effectiveness research using cancer registry and administrative data. The study, led by Gianpaolo Carpinito and colleagues from the University of North Carolina Chapel Hill, aimed to better
Cancer
New research published online in the JNCCN-Journal of the National Comprehensive Cancer Network reveals that individuals with cancer who quit smoking have a much lower risk of dying within two years compared to those who continue smoking. The study, which tracked over 13,000 individuals with cancer, found that the
Stomach cancer
Researchers at the University of Verona in Italy have conducted a study on the impact of frailty on postoperative outcomes and protocol adherence in patients undergoing gastrectomy for gastric cancer. The retrospective multicenter study included 957 patients who underwent gastrectomy within an enhanced recovery protocol (ERP) between 2018 and 2024.
Cancer
Researchers from the University of Texas MD Anderson Cancer Center have made a significant discovery in the field of cancer therapy, developing a new technique to target collagen in tumors. The study, published in the Proceedings of the National Academy of Sciences, found that a specific type of T cell
Cancer
Researchers at Guy's and St Thomas' NHS Foundation Trust and King's College London have explored the clinical potential of CAR T-cell-derived extracellular vesicles (CAR-EVs) as a revolutionary cancer treatment. CAR-EVs are nanovesicles released by CAR T cells, which can play a crucial role in intercellular
