Cancer
Researchers at the University of Valencia have made significant strides in developing a reliable and sensitive cancer detection method. According to a new report, the team has designed and synthesized a near-infrared fluorescent probe (NB-SO3-Leu) derived from the Nile Blue (NB) fluorophore scaffold. The probe's mechanism of action
Cancer
Apollo Cancer Centre (ACC) in Navi Mumbai has successfully treated two patients with made-in-India CAR T-cell therapy, marking a significant milestone in the hospital's commitment to delivering high-quality, life-saving transplant services. The centre has seen remarkable success with 85 Bone Marrow Transplant (BMT) procedures, with a long-term success
Cancer
Researchers from Sichuan University have made a significant discovery in the field of cancer therapy, identifying a new strategy to target B7-H3, an immune-checkpoint molecule overexpressed in several cancer types. The study, published in International Immunopharmacology, found that natural killer (NK) cells, another important part of the cellular immune system,
Cancer
Research has shown that human papillomavirus type 16 (HPV16) positive cancers create a tumor environment that induces antigen-presenting cells to increase IL-23 expression. This cytokine impacts the antitumor cytotoxic T-cell response in HPV16+ cancer. The American Association of Immunologists Careers in Immunology and Nih have provided financial support for this
Cancer
Research from Zhengzhou University has led to the development of an ultrasound-visualized methionine partitioning nano-modulator that aims to improve the efficacy of tumor immunotherapy. This innovative approach involves reducing methionine uptake by tumor cells, suppressing tumor glycolysis, and alleviating the acidic tumor microenvironment. By leveraging ultrasound guidance and liquid-gas phase
Cancer
New research from the Keck School of Medicine of USC has shed light on the mechanisms behind human papillomavirus (HPV)-linked cancers, specifically the role of a signaling protein, Interleukin-23 (IL-23), in undermining the body's defenses. The study found that blocking IL-23 boosts the effectiveness of experimental treatments
Cancer
Researchers have made significant progress in understanding the role of epigenetics in cancer, highlighting its potential as a critical frontier in next-generation cancer immunotherapy. According to a recent study published in Immunologic Research, epigenetic modifications such as DNA methylation, histone modifications, and non-coding RNAs play a crucial role in shaping
Cancer
Researchers at Sichuan University have made a significant breakthrough in cancer immunotherapy, developing a novel platform that synergistically suppresses cancer cell stemness. According to the study, cancer cells with stemness characteristics can evade immune recognition and killing, leading to recurrence and metastasis. To overcome this, the researchers created salinomycin-repurposed endoplasmic
Cancer
Kathy Coleman, a long-time supporter of University Hospitals, has pledged $3.5 million to the University Hospitals Seidman Cancer Center to fuel the future of clinical trials. The gift will enable the center to expand its clinical trials program, tripling patient capacity by 2030 and bringing potentially life-extending treatments to
Cancer
Cancer awareness is set to take center stage in Kolkata during the upcoming Durga Puja celebrations. Several puja committees across the city have decided to host cancer awareness camps at their respective pandals, not only during the festival but also after it. The initiative, spearheaded by Resurrection, a government-registered public
Cancer
Research published in the European Journal of Surgical Oncology has highlighted the growing connection between obesity and gastric cancer. According to the study, obesity is now recognized as a carcinogen, promoting tumourigenesis through endocrine, inflammatory, and mechanical pathways. This association has significant implications for gastrointestinal surgical oncology, increasing cancer incidence,
Cancer
Ryvu Therapeutics, a clinical-stage drug discovery and development company, has entered a strategic agreement with BioNTech to support clinical trials for investigational cancer immunotherapies in Poland. The agreement aims to accelerate site activation and patient enrollment for multiple of BioNTech's priority oncology clinical programs in Poland. Ryvu will
