Cancer
Researchers from Universite Claude Bernard Lyon 1 have made a significant discovery in the field of cancer treatment. According to their study, published in the journal Biochimica et Biophysica Acta, the inhibition of nucleotide excision repair (NER) proteins can increase the efficacy of alkylating agents used to treat various cancers.
Cancer
Researchers from Anhui Medical University have made significant discoveries in the field of immunology and autoimmunity, highlighting the potential of Tyrosine Kinase 2 (TYK2) inhibitors in treating various autoimmune diseases and cancers. The study, published in Bioorganic Chemistry, explored the structure and biological features of TYK2, the JAK/STAT signaling
Cancer
Researchers from Putian University in China have made a significant breakthrough in cancer treatment by developing a nano-photosensitizer that combines chemotherapy and phototherapy to target and kill cancer cells. The innovative nano-photosensitizer, called BAP, uses a single wavelength laser to initiate both photodynamic therapy (PDT) and photothermal therapy (PTT), while
Cancer
Nigel, an avid fundraiser, has dedicated numerous marathons to raising money for good causes, with a special focus on Children with Cancer UK. His tireless efforts have yielded impressive results, with the charity benefiting from an incredible £65,000 in total. Nigel's drive and determination have placed him
Cancer
The 16th annual Dolphins Cancer Challenge (DCC) XVI is set to take place on February 28, 2026, at Hard Rock Stadium's Miami International Autodrome, with a record-breaking goal of surpassing $100 million in cancer research funding for Sylvester Comprehensive Cancer Center. Since its inception in 2010, the DCC
Cancer
Researchers from the University of Torino, Italy, have published a new report on the impact of a rationally designed chemotherapy combination on the generation of hypermutation and immunogenicity in otherwise immune-refractory colorectal and breast cancer mouse models. The study investigated the effects of combining cisplatin and temozolomide on the immune
Cancer
Investigators at Dokuz Eylul University Faculty of Medicine have conducted a study comparing the International metastatic renal cell carcinoma (mRCC) Database Consortium (IMDC), Memorial Sloan Kettering Cancer Center (MSKCC), and Cleveland Clinic Foundation (CCF) risk models in patients with metastatic renal cell cancer who received immunotherapy (IO) and molecular targeted
Cancer
Researchers from the University of Texas MD Anderson Cancer Center have developed a machine learning model that improves survival in advanced non-small cell lung cancer (NSCLC) patients. The model, called A-STEP, uses clinicogenomic data from four cohorts to predict individual benefit from adding chemotherapy to immunotherapy. The study found that
Cancer
A new study published in Frontiers in Oncology suggests that perioperative anesthesia management plays a crucial role in preventing postoperative cancer recurrence and metastasis. The study, conducted by researchers at the School of Anesthesiology in Shandong, People's Republic of China, highlights the immunosuppressive effects of certain anesthesia techniques
Cancer
As Bex Yendall recalls the struggles her mother, Karen, faced with fibromyalgia and advanced-stage lung cancer, it becomes clear that the family's journey was marked by grace, resilience, and the compassionate care provided by Marie Curie. Despite receiving a devastating diagnosis, Karen's calm demeanor and caregiver
Cancer
Researchers at Lanzhou University have developed a CT radiomics model that can predict microsatellite instability (MSI) status and immunotherapy response in gastric cancer patients. The model demonstrates good predictive performance, achieving AUCs of 0.952, 0.835, and 0.879 in the training set and two external testing sets, respectively.
Cancer
A groundbreaking study published in the journal Drug Development Research has uncovered the crucial role of the MYB/IQGAP3 axis in mediating 5-Fluorouracil (5-FU) resistance in gastric cancer (GC) cells. The research, led by Piyao Gao and colleagues from Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine, reveals
