Cancer
A recent study published in Frontiers in Immunology has shed new light on the treatment of locally advanced gastric cancer. Researchers from Nankai University have developed and validated a nomogram model to predict pathological complete response (pCR) in patients receiving neoadjuvant chemotherapy and immunotherapy (NICT). The study, which enrolled 456
Cancer
Researchers at Sichuan University have published a comprehensive review on the role of extracellular vesicles (EVs) in cancer diagnosis and therapy. According to the study, EVs have emerged as promising non-invasive biomarkers in oncology, offering innovative biomarkers and therapeutic targets for improved diagnosis and treatment of cancer. The review highlights
Cancer
Researchers at Peking University Third Hospital have conducted a phase 1b study to evaluate the safety and efficacy of stereotactic body radiotherapy (SBRT) combined with cadonilimab, a humanized immunoglobulin G1 bispecific antibody targeting programmed cell death protein 1 (PD-1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). The study involved 63 patients
Cancer
Peter MacCallum Cancer Centre, a leading cancer centre in Australia, is working to improve the cultural safety of First Nations people receiving cancer care through two new projects. The projects aim to foster new connections between healthcare providers and Aboriginal-led organisations, ultimately supporting better outcomes for First Nations patients. The
Cancer
A recent study from Dong-A University College of Medicine in Busan, South Korea, has explored the association between insulin resistance and gastric cancer in South Korean individuals. The research, published in the journal Medicine, analyzed claims data from the National Health Insurance Service and a cohort of 316,129 individuals
Cancer
Cancer gene therapy has made significant advancements in recent years, with researchers exploring various methods to target and treat cancerous tumors. A new study from the University of Tabuk in Saudi Arabia has shed light on the potential of nanoparticles in stromal reprogramming, a process crucial for tumor expansion and
Cancer
Research from Mahidol University in Bangkok, Thailand, has highlighted the potential of Chimeric Antigen Receptor (CAR)-based immunotherapy in transforming cancer treatment, specifically for hematologic malignancies like acute lymphoblastic leukemia and diffuse large B-cell lymphoma. Innovations in CAR design have enhanced T cell persistence and antitumor efficacy, but significant challenges
Cancer
Researchers from Soochow University in China have made a significant breakthrough in cancer immunotherapy, developing a potent nanoinducer that boosts immunogenic cell death and antitumor immunity in solid tumors. The study, published in the journal Chemical Engineering Journal, highlights the potential of this new treatment approach in augmenting immunotherapy in
Cancer
Research conducted at the Meshalkin National Medical Research Center has highlighted the complexities of radiation-induced heart disease in patients with chest cancer. According to the study, radiation therapy can cause a range of heart-related complications, including pericarditis, cardiomyopathy, coronary artery disease, acquired valvular heart disease, and arrhythmias. The study aimed
Cancer
Researchers at Central South University have published a comprehensive review on the mechanisms of immune evasion in cancer and potential therapeutic approaches. The review highlights the complex processes by which tumors evade immune surveillance, including tumor-induced immune suppression, immune checkpoint regulation, and genetic and epigenetic influences. The study also emphasizes
Cancer
Cancer immunotherapy has shown significant promise in the treatment of various cancers, but a new study highlights a growing concern: the risk of venous thromboembolism (VTE). According to investigators at Emory University, the incidence of VTE in patients receiving immunotherapies for cancer is a significant complication, with distinct pathophysiological mechanisms
Cancer
A team of researchers from the University Grenoble-Alpes has made significant advancements in the field of biotechnology, particularly in cancer gene therapy. Their study, published in the European Journal of Pharmaceutical Sciences, explores the potential of photodynamic drug delivery systems in cancer treatment. The researchers propose a novel approach using
