Cancer
Immunophotonics, a clinical-stage biotech company, has announced the completion of the INJECTABL-1 multicenter Phase 1b/2a clinical trial of its proprietary glycan polymer, IP-001, for advanced solid tumors. The trial, conducted in five countries, aimed to evaluate the systemic immune-mediated anti-cancer effects of IP-001 following tumor ablation. The company reports
Cancer
Scientists at UCLA have demonstrated a novel approach to treating cancer by combining genetically engineered T cells with stem cells, resulting in the production of cancer-fighting immune cells in humans. This groundbreaking study, published in Nature Communications, represents a new way to deliver immunotherapy, with the potential to offer longer-lasting
Cancer
Researchers at Genentech Inc. have successfully engineered interleukin-18 (IL-18), a pro-inflammatory cytokine, to enhance its stability, half-life, and manufacturability, potentially paving the way for its use in cancer immunotherapy. The engineered variant, disulfide-stabilized IL-18 Fc-fusion (dsIL-18-Fc), demonstrated improved stability and mammalian host cell production yields compared to the wild-type cytokine.
Cancer
Researchers from the University of Chicago have developed a new platform for cancer immunotherapy using chimeric antigen receptor (CAR) T cell therapy. This innovative approach has shown promise in treating hematological cancer, while addressing challenges such as antigen loss, toxicity, and complex manufacturing. The new platform, known as the CAR-fragment
Cancer
Researchers at the University of Texas MD Anderson Cancer Center have made a groundbreaking discovery in the field of life sciences, demonstrating that increasing tumor oxygenation can promote T cell infiltration and tumor control by immune checkpoint blockade. This breakthrough has significant implications for the development of new cancer treatments.
Cancer
Researchers at the University of Cincinnati have developed a novel combination therapy for treating cancer metastases, which shows promise in addressing the long-standing challenge of treating the secondary growths that often accompany primary tumors. The therapy, which incorporates a combination of vascularization and/or tissue remodeling inhibitors, suppressors of oxidative
Cancer
A recent study published in the Blood Cancer Journal has shed light on the importance of immune reconstitution in vaccine responses post-CAR T therapy for patients with hematological malignancies. Researchers at Memorial Sloan-Kettering Cancer Center conducted a single-center, retrospective study analyzing vaccine responses in 73 patients who received post-CAR T
Cancer
Researchers from Imam Mohammad Ibn Saud Islamic University in Riyadh, Saudi Arabia, have conducted a study that sheds light on the role of glyoxalase 1 (GLO-1) in various types of cancer cells. The study, published in Frontiers in Oncology, found that GLO-1 is a significant biomarker across multiple cancers that
Cancer
In a bid to improve cancer awareness and encourage earlier diagnosis among Leicester's Black and ethnic minority communities, Consultant Medical Oncologist Olubukola Ayodele and Ear, Nose and Throat Consultant Oladejo Olaleye are leading a groundbreaking programme called 'Cancer Conversations'. The initiative brings cancer education directly into
Cancer
A new study by the American Cancer Society has found that firefighters are at a higher risk of developing certain types of cancer, including skin, kidney, and lung cancer, compared to men working in other occupations. The study, which tracked nearly 470,000 participants over 36 years, found that firefighters
Cancer
Scientists at the ADLM 2025 conference have presented studies highlighting two innovative tests that could revolutionize women's healthcare. A self-collection test for human papillomavirus (HPV) has shown promising results in underserved communities, while a minimally invasive test for endometrial cancer aims to reduce the number of invasive procedures
Cancer
Research from the University of Gadjah Mada in Yogyakarta, Indonesia has shed light on the potential of soursop leaf extracts as a co-chemotherapy agent in treating various types of cancer. The study, published in the Journal of Pharmaceutical Science and Clinical Research, highlights the phytochemical content of the soursop leaf
