Cancer
Researchers at CureLab Oncology have announced that their DNA plasmid therapy, Elenagen, has shown a 90% success rate in alleviating chronic pain in dogs with osteoarthritis. This breakthrough therapy, which was previously shown to be safe and effective against lethal ovarian cancer, reprograms aged or dysfunctional mesenchymal stem cells to
Cancer
As the two companies embark on a decade-long partnership, they are leveraging diagnostic innovations to accelerate the development of personalized cancer treatments. From its inception in 2017, the collaboration has evolved into a comprehensive diagnostic partnership, with bioMérieux's BACT/ALERT systems and VITEK MS for microbial identification supporting
Cancer
Researchers at the Sloan Kettering Institute for Cancer Research have developed a rapid and effective workflow for verifying genome-edited human pluripotent stem cells (hPSCs) targeting unexpressed genes using CRISPR-mediated transcriptional activation (CRISPRa). This approach bypasses the need for complex and time-intensive differentiation to induce target gene expression, allowing for the
Cancer
Pioneering research by investigators at Tehran University of Medical Sciences has made significant progress in understanding the role of inhibitory receptors in the treatment of gastric cancer. By blocking the NK group-2 member-A (NKG2A) receptor, researchers have demonstrated the enhancement of tumor immunity in natural killer (NK) cells, paving the
Cancer
Research conducted at Dalian Medical University in Dalian, People's Republic of China, has led to the development of a novel cascade-responsive nanoplatform for synergistic cancer therapy. This platform, tailor-made to address the complex characteristics of the tumor microenvironment (TME), integrates photodynamic therapy (PDT), chemotherapy, and immunotherapy to achieve
Cancer
Researchers at Northwestern University have discovered a groundbreaking approach to cancer treatment that doubles the effectiveness of chemotherapy in treatment-resistant cancer. By understanding the intricate organization of genetic material, called chromatin, the team developed a new strategy to prevent cancer cells from adapting and evading treatment. This approach uses an
Cancer
Research from Hangzhou Normal University, in collaboration with various institutions, has shed light on potential therapeutic targets for gastric cancer, a disease with poor prognosis and limited treatment options. The study focused on understanding the inflammatory and protein-protein interaction hub networks that drive tumor progression. By analyzing gene expression and
Cancer
Researchers at the City of Hope National Medical Center have made a significant discovery in cancer gene therapy, developing a new cell-selective and double-stranded STAT3 antisense oligonucleotide (CpG-STAT3dsASO) that targets human/mouse glioma cells and immune cells, but not T cells. This innovative approach has shown promise in reducing progression
Cancer
Scientists at Fudan University in Shanghai, China, have made a groundbreaking discovery in cancer therapy, finding that high-intensity focused ultrasound (HIFU) can convert "cold" tumors into "hot" ones, making them more responsive to immunotherapy. The study, published in Acta Pharmaceutica Sinica B, investigated the role of
Cancer
Researchers have made a significant breakthrough in the field of cancer immunotherapy, utilizing optogenetics to refine the precision and adaptability of this treatment approach. A new study published in Essays in Biochemistry reveals the potential of optogenetics to improve the safety and efficacy of cancer immunotherapy by enabling targeted modulation
Cancer
Godavari Biorefineries, through its clinical-stage biotech division Sathgen Therapeutics, has been granted a patent by the China National Intellectual Property Administration (CNIPA) for its novel anti-cancer molecule, HYDROXY-1, 4-NAPHTHALENEDIONE. This patent covers a novel class of compounds that have exhibited strong inhibitory effects on cancer and cancer stem cells in
Cancer
Researchers from the National University of Singapore have made a groundbreaking discovery in the field of cancer gene therapy. According to their study, a new therapeutic strategy using extracellular vesicles (EVs) can effectively inhibit KRAS mutants and activate the RIG-I pathway, leading to a robust anti-tumor immune response. This approach
