Cancer

Cancer

Nutrient-Gene Therapy Shows Promise in Enhancing CAR T-Cell Function and Overcoming Barriers in the Tumor Microenvironment

Cancer immunotherapy has revolutionized the treatment landscape of both hematological and solid cancers. However, despite initial success, T-cell-based adoptive cell transfer (ACT) therapies have been hindered by several obstacles, including a lack of antigen specificity, poor long-term survival of transplanted T cells, and a hostile tumor microenvironment. A team of

Cancer

Targeted Gene Delivery to MCF-7 Cells Via Polyspermine-Peg-Glucose/DNA Nanoparticles: A Breakthrough in Cancer Gene Therapy

Research conducted at Islamic Azad University in Ardebil, Iran, has made significant strides in cancer gene therapy by successfully developing polyspermine-peg-glucose/DNA nanoparticles for targeted gene delivery to MCF-7 cells. This innovative approach utilizes cationic polymers to electrostatically interact with negatively charged DNA, enabling efficient and targeted delivery of genetic

Cancer

Breakthroughs in Sorafenib Delivery Systems Enhance Therapeutic Potential for Cancer Treatment

Scientists at Lomonosov Moscow State University have made significant advancements in the development of sorafenib delivery systems, a proven treatment for kidney cancer, to improve its bioavailability and expand its therapeutic potential to other oncological diseases. By leveraging biopolymers and supramolecular assemblies, researchers have created more sophisticated delivery systems with