Cancer
Recent research conducted by investigators at the University of Texas MD Anderson Cancer Center has shed new light on the role of germline genetic aberrations in predicting toxicity and efficacy in patients with large B-cell lymphoma treated with chimeric antigen receptor T-cell therapy (CART). The study, published in the Journal
Cancer
Ben Weedon, a 50-year-old fire service veteran and ultra-marathon runner, has been diagnosed with Stage 2 Prostate Cancer, but has since made a good recovery after undergoing surgery. Recognizing his fortunate position, Ben wants to give back to the community that supported him throughout his journey. He will be participating
Cancer
Researchers from Chongqing Medical University in China have made a significant discovery in the field of cancer immunotherapy. A new report published in Advanced Healthcare Materials reveals that a novel metal-polyphenol network-coated human serum albumin nanoplatform, dubbed IMT@H, has shown remarkable efficacy in treating HPV-associated malignancies. The nanovaccine combination
Cancer
Researchers from Osaka, Japan have identified a promising biomarker for gastric cancer, which could potentially aid in predicting the effectiveness of a specific immunotherapy treatment. The study, conducted by the Osaka International Cancer Institute, found that a tumor-infiltrating lymphocyte (TIL) biomarker was predictive of the efficacy of nivolumab monotherapy in
Cancer
Researchers from the University of California have developed a new model system to perform genome-wide in vivo CRISPR screens to identify genetic modifiers of T cell activity in the tumor microenvironment. In a groundbreaking study, the team conducted two genome-wide CRISPR knockout screens to identify genes regulating T cell intratumoral
Cancer
Researchers at the University of Mainz have made a groundbreaking discovery in the field of cancer gene therapy, introducing a novel ATP-dissipative delivery system that exploits the energy currency of life to selectively deliver therapeutic oligonucleotides to cancer cells. This innovative approach utilizes artificial cells that transiently eject DNA signal
Cancer
The global Cancer Gene Therapy Market is poised to experience significant growth, driven by factors such as increased cancer malignancy, research, and clinical trials on CAR-T and other gene therapies. The U.S. market is expected to reach USD 8.30 billion by 2032, growing at a CAGR of 19.
Cancer
As Alan prepares to embark on a once-in-a-lifetime trek to Cambodia's majestic Angkor Wat temple complex, he reflects on a remarkable year that has been filled with love, health challenges, and a renewed sense of purpose. This 70-year-old grandfather, who celebrated his 70th birthday just weeks after marrying
Cancer
Researchers from Guru Nanak Dev University have made groundbreaking findings in the field of cancer gene therapy, particularly in the development of nano-immunoconjugates. These innovative molecules represent a next-generation strategy in the treatment of cancer by harnessing the body's immune system to recognize and eradicate tumor cells. The
Cancer
A new study has shed light on the key mechanisms driving gastric cancer progression, immune evasion, and treatment resistance. According to the research, glucose metabolism reprogramming plays a pivotal role in promoting tumor progression, immune evasion, and treatment resistance in gastric cancer. The study, conducted by a team of researchers
Cancer
A recent meta-analysis published in the International Journal of Surgery has revealed new insights into the efficacy and safety of immunotherapy-based neoadjuvant regimens for locally advanced gastric cancer (LAGC). The study, conducted by a team of researchers from Capital Medical University in Beijing, China, aimed to evaluate the antitumor effects
Cancer
Scientists at the University of Texas Southwestern Medical Center have shed new light on the mechanisms of cancer immunotherapy by mapping the clonal expansion and differentiation of neoantigen-specific CD8+ T cells in the tumor and draining lymph node in mouse prostate cancer. The research, published in Cancer Immunology Research, reveals
