Cells (Biology)
Researchers from the Max-Planck-Institute for Multidisciplinary Sciences have made a significant discovery in the field of cell biology, shedding light on the molecular targets of Mos-MAPK and its role in meiotic cell cycle and asymmetric oocyte divisions. The study, published in the Journal of Cell Biology, used starfish oocytes to
Biochemistry
Researchers at the University of Liverpool have highlighted the importance of labile phosphorylation in mammalian signalling networks, shedding light on a previously understudied area of biochemistry. The study, published in Biochemical Society Transactions, reveals that labile phosphorylation sites (LaPhs) play diverse roles in mammalian cells, distinct from the highly stable
Cells (Biology)
Researchers at Durham University have made a groundbreaking discovery in the field of cell biology, uncovering a novel mechanism in chromosome segregation during anaphase A in Caenorhabditis elegans embryos. According to the study, published in the Journal of Cell Biology, this mechanism is driven by the kinesin-13 KLP-7MCAK and opposed
Biochemistry
Researchers at the University of Liverpool have highlighted the importance of labile phosphorylation in mammalian signalling networks, shedding light on a previously understudied area of biochemistry. The study, published in Biochemical Society Transactions, reveals that labile phosphorylation sites (LaPhs) play diverse roles in mammalian cells, distinct from the highly stable
Cells (Biology)
Scientists from the Department of Microbiology at the Icahn School of Medicine at Mount Sinai have been awarded a significant grant of up to $11.8 million from the Advanced Research Projects Agency for Health (ARPA-H) to develop a comprehensive map of the critical points inside human cells that viruses
Cells (Biology)
A recent study published in the Journal of Cell Biology has shed new light on the dynamics of the endosomal sorting complex required for transport (ESCRT) machinery in mammalian cells. Researchers at the University of Wisconsin School of Medicine and Public Health conducted the study, which was funded by the
Cells (Biology)
Research by Universite de Haute-Alsace has shed light on the significance of curvature in biology, revealing its ubiquitous presence in structures at every scale and its diverse roles in processes like membrane dynamics and tissue organization. The study, published in BMC Biology, delves into the mechanisms by which membrane curvature
Antiviral agents
Researchers at the Icahn School of Medicine at Mount Sinai have been awarded up to $11.8 million from the Advanced Research Projects Agency for Health (ARPA-H) to develop a new approach to antiviral therapy. The project, called Closing the Doors to All Pathogens Through Integrated Digital Experiments (DOORs), aims
Biological products
Receding gums, or gingival recession, is a common condition affecting millions worldwide, with new dental research shedding light on its development, reversal, and potential future therapies. The condition occurs when gum tissue pulls away from the tooth, exposing the root surface and increasing the risk of sensitivity, cavity formation, and
Antigens
New research published in the Proceedings of the National Academy of Sciences has shed light on the intricate network of thymic hematopoietic antigen-presenting cells, revealing unexpected heterogeneity and tissue-specific properties. The study, conducted by researchers at the St. Vincent's Institute of Medical Research, has identified various cell lineages,
Scientists
Scientists at the University of Southern California (USC) have developed a revolutionary method for generating three-dimensional models of the entire DNA strand of a cell, known as a genome. This breakthrough allows researchers to gain a better understanding of the structure and function of the genome, which plays a crucial
Scientists
Research investigators published a study in The American Journal of Pathology, concluding that Sox4 expression has significant prognostic implications in human cutaneous melanoma. The study evaluated Sox4 expression in 180 melanocytic lesions, revealing a remarkable reduction in metastatic melanoma compared to dysplastic nevi. This reduction in Sox4 expression was found
