Cancer
Despite significant advances in treating multiple myeloma, older patients, males, and those from underrepresented racial and ethnic groups continue to face disparate survival rates. Research published in the British Journal of Haematology tracked the survival rates of 50,288 adults diagnosed with multiple myeloma between 2000 and 2019. The study
Cancer
In a recent study published in the Lancet Oncology, researchers at the Cleveland Clinic Foundation found that the combination of enfortumab vedotin plus pembrolizumab significantly improved survival outcomes for patients with previously untreated locally advanced or metastatic urothelial cancer. The study, which enrolled 886 patients, found that the treatment combination
Cancer
Researchers from Guangxi Normal University have made significant strides in cancer gene therapy, developing a high-efficacy and low-toxicity cobalt(II) agent capable of targeting and inhibiting tumor growth. This innovative approach leverages the tumor microenvironment and liposomes to deliver the cobalt(II) complex, C3, which has shown impressive cytotoxicity against
Cancer
A recent review published in the Chinese Medical Journal has outlined the advancements in nanocarrier-mediated cancer therapy, highlighting the potential of these transformative modalities in improving treatment efficacy and reducing adverse effects. Researchers from the Inner Mongolia Medical University have emphasized the importance of developing safer and more precisely targeted
Cancer
As a mum of two young boys, Maxine Hughes thought she had it all together, but behind the scenes, she was secretly battling an aggressive form of cancer. Despite her diagnosis of triple negative cancer, she continued to work as a translator on Disney's "Welcome to Wrexham&
Cancer
A team of researchers led by cancer genetics experts at the University of Birmingham has discovered a new hereditary condition, DIAL syndrome, which affects patients' ability to repair DNA. This condition leaves them at a greater risk of developing blood cancer and impairs their ability to repair damage caused
Cancer
Researchers at Heidelberg University have made new discoveries about the impact of Metformin on HPV-positive cancer cells, shedding light on its potential therapeutic uses. The study found that Metformin's effects on cancer cells were complex and influenced by various factors, including the presence of chemotherapeutic agents. The findings
Cancer
Research conducted by scientists at Ewha Womans University in Seoul, South Korea, has explored the potential of sodium butyrate (NaB) in overcoming acquired resistance to 5-fluorouracil (5-FU), a first-line chemotherapy for gastric cancer (GC). The study aimed to investigate the molecular mechanisms of NaB in GC cell lines, including its
Cancer
A recent study aimed to provide a comprehensive guideline for the evaluation of cardiovascular toxicity in pediatric cancer survivors using cardiac magnetic resonance imaging (MRI). The study, conducted by researchers at the University of Tennessee, aimed to standardize the approach to cardiac MRI assessment in this population, focusing on the
Cancer
Researchers at the Department of Medical Oncology conducted an open-label, single-arm Phase II trial to evaluate the effectiveness and safety profile of first-line immune checkpoint inhibitors combined with chemotherapy in pulmonary sarcomatoid carcinoma (PSC). The study found that the combination of immune checkpoint inhibitors with chemotherapy showed robust efficacy alongside
Cancer
Researchers at Fujian University of Traditional Chinese Medicine have discovered that baicalin, a compound found in Chinese herbal medicines, can reverse multidrug resistance in human hepatocellular carcinoma (HCC) cells. The study found that baicalin increased the accumulation of chemotherapy drugs and induced apoptosis and autophagy in resistant HCC cells by
Cancer
Scientists at the Cancer Hospital in Beijing, China, have discovered that a combination of cytokine-induced killer (CIK) cell therapy and chemotherapy, with or without the immune checkpoint inhibitor (ICI) cadonilimab, can effectively inhibit the growth of human gastric cancer in a mouse xenograft tumor model. This research, published in the
