Child health

Child health

Maldives Achieves Historic "Triple Elimination" of Hepatitis B, HIV, and Syphilis Transmission from Mother to Child

The World Health Organization (WHO) has validated the Maldives' achievement of eliminating the transmission of hepatitis B, HIV, and syphilis from mother to child, making it the first country in the world to achieve this milestone. This achievement is a testament to the country's strong political will

Pediatrics

MannKind Corporation's Afrezza Receives FDA Approval sBLA for Pediatric Patients

The U.S. Food and Drug Administration (FDA) has accepted the supplemental biologics license application (sBLA) from MannKind Corporation for Afrezza (insulin human) Inhalation Powder in children and adolescents living with type 1 or type 2 diabetes. The application has been assigned a Prescription Drug User Fee Act (PDUFA) target

Pediatrics

Rare Vitamin B12 Deficiency Manifestation in Pediatric Patient with Autism

A recent case report highlighted a rare and severe manifestation of vitamin B12 deficiency in a 12-year-old male with autism spectrum disorder. The patient presented with fever, night sweats, and weight loss, and laboratory tests revealed severe neutropenia and hemolytic anemia. Dietary history revealed significant food restriction over the preceding

Pediatrics

Rare Tracheal Bronchus in Pediatric Patient with Noonan Syndrome Leads to Lung Abscess

A 13-year-old male patient with Noonan syndrome, pulmonary valve stenosis, and von Willebrand disease presented with chest pain, fever, and chronic vomiting. Computed tomography revealed a right upper lobe pulmonary cavitation, which was later diagnosed as a cavitary lung abscess secondary to a tracheal bronchus. The patient was treated with

Pediatrics

Fluoroquinolone Susceptibility and Comparative Outcomes of Gram-negative Bloodstream Infection in Pediatric Patients with Hematologic Malignancy

A new study from the Children's Hospital of Philadelphia has shed light on the impact of fluoroquinolone non-susceptible (FQN-NS) gram-negative (GN) bloodstream infections (BSI) on outcomes in pediatric patients with hematologic malignancies. Researchers found that FQN-NS BSI was associated with higher 30-day all-cause mortality and sepsis-related mortality, although

Pediatrics

Rare Case of Langerhans-Cell Histiocytosis in Pediatric Patient with Lynch Syndrome Highlighted by Researchers

A unique case of Langerhans-cell histiocytosis (LCH) in a pediatric patient with Lynch syndrome has been reported by researchers at Memorial Sloan-Kettering Cancer Center. The study, published in the JBJS Case Connector, details the treatment and outcome of a 12-year-old boy who developed osteosarcoma and LCH after chemotherapy and pembrolizumab.

Child health

Maldives Achieves Historic "Triple Elimination" of Mother-to-Child Transmission of HIV, Syphilis, and Hepatitis B

In a groundbreaking public health achievement, the Maldives has become the first country in the world to eliminate mother-to-child transmission of hepatitis B, HIV, and syphilis. This significant milestone was validated by the World Health Organization (WHO) on October 13. The Maldives' achievement is a testament to its strong

Pediatrics

Secondary Findings in Pediatric Genomic Testing: Insights from a Turkish Cohort

A new report from a Turkish study has shed light on the management of secondary findings (SFs) in pediatric populations undergoing whole exome and genome sequencing. Researchers from the University of Health Sciences analyzed data from 980 Turkish pediatric patients, examining the frequency, characteristics, and familial implications of SFs. The

Pediatrics

New Study Reveals Best Cut-Off for ALT to Predict Metabolic Dysfunction-Associated Steatotic Liver Disease in Youths with Obesity

Researchers from the University of Campania Luigi Vanvitelli have published a study in the Journal of Pediatric Gastroenterology and Nutrition, investigating the best cut-off of alanine aminotransferase (ALT) to predict metabolic dysfunction-associated steatotic liver disease (MASLD) in youths with overweight/obesity. The multicenter, cross-sectional study analyzed data from 2813 youths

Pediatrics

Immune Checkpoint Inhibitors Show Promise in Pediatric Liver Cancer Treatment

Researchers at the First Affiliated Hospital of Gannan Medical University in Jiangxi, People's Republic of China, have reported two cases of pathologically confirmed pediatric hepatocellular carcinoma (HCC) treated with immune checkpoint inhibitors (ICIs). The study, published in Frontiers in Oncology, highlights the potential of ICIs in pediatric HCC

Pediatrics

Insights into the Molecular Mechanism of Pulmonary Vein Stenosis in Pediatric Patients with Congenital Heart Disease

A new study on pediatric pulmonary vein stenosis (PVS) has been published, providing a comprehensive understanding of the molecular mechanisms underlying the development and trajectory of PVS. The research, conducted at Texas Children's Hospital, reveals that aggressive primary pulmonary vein stenosis (PPVS) is associated with changes in the

Pediatrics

Pediatric Traumatic Brain Injury Rates High in Low-Income Countries

A new study has shed light on the high rates of pediatric traumatic brain injury (TBI) in low- and middle-income countries, where access to adequate medical care is often limited. Researchers from the University of Minnesota Twin Cities found that decompressive craniectomy (DC), a surgical procedure that removes a portion