Clinical trials - Strategic Insights Report (Page 4)

Clinical trials

Ensuring Quality and Interpretability of Progression Free Survival and Overall Survival in Oncology Clinical Trials

In a detailed study, researchers have shed light on the complexities of measuring the effectiveness of cancer treatments through progression-free survival (PFS) and overall survival (OS) endpoints. These endpoints, crucial in assessing therapeutic efficacy in oncology drug development, are frequently compromised by various factors, including protocol design, intercurrent events, and

Clinical trials

Oncoinvent ASA Announces Positive Final 24-Month Follow-Up Results from Phase 1 Clinical Trial of Radspherin for Platinum-Sensitive Recurrent Ovarian Cancer

Oncoinvent ASA, a clinical-stage radiopharmaceutical company, has announced positive final 24-month follow-up results from its Phase 1 clinical trial evaluating Radspherin in patients with platinum-sensitive recurrent ovarian cancer and peritoneal carcinomatosis. The trial aimed to eliminate post-surgery micro-metastases and prevent or delay peritoneal recurrence using direct intraperitoneal targeting with the

Clinical trials

Effective Mosquito Surveillance through Digital Technologies and Community Involvement

Researchers at the Ifakara Health Institute have reported new data on malaria surveillance methods, highlighting the need for new technologies and approaches to collect data and design control tools. The study utilized digital technologies, including the HumBug acoustic sensor and the MozzWear app, to detect and identify host-seeking mosquitoes. A

Artificial intelligence

Artificial Intelligence Transforms Clinical Research and Scientific Writing

Artificial intelligence is revolutionizing the field of clinical research and scientific writing, offering innovative solutions to address inefficiencies in trial design, patient recruitment, and manuscript development. Research from Yale University School of Medicine has explored the applications of artificial intelligence in patient matching, endpoint design and predictive trial outcomes, and

Clinical trials

Shifting Perspectives on Voice Hearing: A Historical and Personal Analysis

Researchers have made significant strides in understanding the nature of voice hearing, shifting from a medical view of it as a psychotic symptom to a dissociative experience. Historically, voice hearing was classified as a core symptom of schizophrenia in the late 20th century, but an alternative paradigm emerged through the

Biological pest control

Biocontrol Efficacy Against Heterobasidion Irregulare Infection Demonstrated

Research published in Forest Ecology and Management has demonstrated the efficacy of Phlebiopsis gigantea as a biocontrol agent against Heterobasidion irregulare, a root disease affecting coniferous forests in the Pacific western US. The study, conducted by a team of researchers from the University of California Berkeley, evaluated the growth and

Associations

Kairos Pharma Presents Positive Interim Efficacy Data on Combination Therapy of ENV-105 and Apalutamide in Metastatic Castration-Resistant Prostate Cancer

Kairos Pharma, Ltd., a clinical-stage biopharmaceutical company, has presented positive interim efficacy data from its ongoing Phase 2 clinical trial of ENV-105 (carotuximab) in patients with metastatic castration-resistant prostate cancer (mCRPC) at the European Society of Medical Oncologists meeting in Berlin, Germany. The data highlights the potential value of combination

Clinical trials

Essential Tremor Pipeline Report 2025: Breakthrough Therapies and Emerging Players

As of October 20, 2025, DelveInsight's comprehensive Essential Tremor Pipeline Insight report highlights the dynamic pipeline landscape, featuring 7+ companies and 10+ pipeline drugs being developed for the treatment of essential tremor. The report provides an in-depth analysis of the pipeline therapies, including their mechanism of action, clinical

Clinical trials

Promising Results for Oncolytic Virotherapy in Treating Recurrent Head and Neck Cancer

Research findings have shed light on the potential of oncolytic virotherapy in treating recurrent head and neck cancer. A recent study published in Virus Research has demonstrated the efficacy and safety of a novel therapeutic approach using VT1093, an oncolytic recombinant herpes simplex virus type 1 engineered to express a

Clinical trials

Massage Therapy Reduces Hospitalization Time in Newborns with Hyperbilirubinemia

Investigators at Babol University of Medical Sciences, Iran, conducted a randomized clinical trial to compare the effects of massage, chicory bath, and phototherapy on bilirubin levels in term newborns. The study, published in BMC Pediatrics, found that massage therapy combined with phototherapy was more effective in reducing the length of

Clinical trials

Parental Consent in Neonatal Clinical Studies: New Insights

A new study published in Acta Paediatrica has shed light on the reasons behind parental decline of participation in neonatal clinical studies. The research, conducted between June 2022 and April 2023, aimed to explore the factors influencing parents' decisions to decline participation in a study investigating the transfer of

Clinical trials

Inclusion of Pregnant and Lactating Persons in Clinical Trials Gains Momentum Internationally

Researchers have highlighted the need for more representative and inclusive clinical trials that account for the unique needs of pregnant and lactating individuals. According to a recent study, there is a lack of knowledge among health care providers and patients about clinical trials during pregnancy, making it challenging to engage

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