COVID-19

COVID-19

Breakthrough in COVID-19 Vaccine Research: Robust Mucosal Immune Response Against Diverse SARS-CoV-2 Variants

Researchers at Sun Yat-sen University have developed a novel nanoparticle vaccine, FP-HR5-NP, which has shown remarkable efficacy in eliciting robust mucosal and systemic immune responses against diverse SARS-CoV-2 variants, including Delta and Omicron. Administered intranasally, the vaccine triggered the production of high titers of FP- and HR5-specific IgG antibodies, as

COVID-19

Engineered Antiviral Platform Shows Promise in Fighting COVID-19

Researchers at Sungkyunkwan University have engineered an antiviral platform using filamentous bacteriophages conjugated with multivalent 9-O-acetylated sialic acid ligands (Ac-SLPhage) to target conserved viral entry pathways of human coronavirus OC43 (HCoV-OC43), a surrogate for SARS-CoV-2. This nanomaterial competitively blocks viral attachment through high-affinity interactions with host sialic acid receptors, while