Depression (Mood disorder)
A new study, published in the Depression and Anxiety journal, has explored the relationship between age at first live birth and depression among women in the United States. The researchers analyzed data from the National Health and Nutritional Examination Surveys (NHANES) from 2005 to 2018, involving 10,399 participants. The
Depression (Mood disorder)
Research has been conducted to determine serum concentrations of selective serotonin reuptake inhibitors (SSRIs) and atypical antipsychotics in children and adolescents. The study, led by Xenia M. Hart, aimed to provide guidance for the definition of therapeutic reference ranges in this age group. The researchers collected serum concentrations of various
Depression (Mood disorder)
Researchers at Xi'an People's Hospital in China have made a significant discovery in the treatment of depression. By developing an innovative affinity chromatography platform, they have identified a novel selective serotonin reuptake inhibitor (SSRI) from the natural product Cyperus rotundus. This new compound, a-cyperone, has been
Depression (Mood disorder)
Recent research from Frederiksberg Hospital has shed new light on the relationship between brain structure, cognitive function, and suicidal behavior in patients with mood disorders. The study aimed to replicate the role of the ventromedial prefrontal cortex (vmPFC) in suicidal behavior and examine cognitive domains that may be impaired in
Depression (Mood disorder)
Researchers from University Hospital Montpellier, France have conducted a study to better understand the biological mechanisms underlying depression and recent suicide attempts. The study compared the immunological profiles of patients with major depressive episodes (MDE) with and without a recent suicide attempt (SA) to those of healthy controls. The results,
Depression (Mood disorder)
Alto Neuroscience has announced plans to expedite the development of ALTO-207, a novel treatment for treatment-resistant depression, following a successful meeting with the FDA. The company has secured $50 million in private placement financing, which will enable it to initiate a Phase 3 study by early 2027. Positive results from
Depression (Mood disorder)
Alto Neuroscience, a clinical-stage biopharmaceutical company, has announced the successful completion of a private placement financing (PIPE) with gross proceeds of approximately $50 million. The financing was led by Perceptive Advisors, with participation from new and existing institutional investors. Alto plans to use the proceeds to accelerate the development of
Depression (Mood disorder)
Research conducted by a team of international scientists reveals a significant association between physical inactivity and depressive symptoms in older adults across high-income and low-and-middle-income countries. The study, published in the Journal of Affective Disorders, analyzed data from 127,580 individuals aged 60 and above from 32 countries between 2011
Depression (Mood disorder)
Research published in a recent study from the Beijing Union University explores the interplay between working hours, internet use, and depressive symptoms among Chinese workers. The study utilized a two-wave longitudinal dataset from the China Family Panel Studies (CFPS) spanning 2016 to 2018, involving 4,900 workers aged 18-70. The
Depression (Mood disorder)
New research from Northwestern University has shed light on the neural mechanisms underlying depression in adolescents. A study published in the Journal of Digital Psychiatry and Neuroscience has found that adolescents with remitted depression exhibit abnormal brain connectivity patterns, particularly in the theta and delta frequency bands. This study has
Depression (Mood disorder)
Researchers from Riga Stradins University conducted a study to investigate the longitudinal, bidirectional associations between psychological well-being and depressive symptoms among older adults in the Baltic States. The study used a cross-lagged panel model to analyze responses from 5,874 individuals aged 50 and above in Estonia, Latvia, and Lithuania.
Depression (Mood disorder)
Research conducted at Wenzhou Seventh People's Hospital in Zhejiang, People's Republic of China, evaluated the effectiveness of a tripartite biopsychosocial intervention program on mental health and quality of life in elderly patients with depression secondary to geriatric diseases. The study involved 166 elderly patients, who were
