Endocrinology
Researchers have shed new light on the function of neuronal gluco-sensing in diabetes, a phenomenon where specialized cells in the brain use glucose as a signaling molecule to regulate energy homeostasis and other biological functions. Investigation by Barry E. Levin and his team at New Jersey Medical School has highlighted
Endocrinology
In a recent study published in Angiology, researchers in Greece investigated left ventricular function in 24 elderly patients with type 2 diabetes, who were asymptomatic and had no history of hypertension, coronary or valvular heart disease. The study found that left ventricular systolic and diastolic indices were impaired in these
Endocrinology
Nastech Pharmaceutical Company Inc. has announced the signing of separate agreements with two undisclosed research partners to evaluate the development of proprietary formulations for the nasal delivery of compounds useful for the treatment of type 2 diabetes and Alzheimer disease. The company will utilize its proprietary Tight Junction technology to
Endocrinology
The international medical community gathered at the 30th Annual Meeting of the International Society for Paediatric & Adolescent Diabetes (ISPAD 2004) in Singapore expressed concern over the growing problem of type 2 diabetes in children, particularly in the Asia-Pacific region. Professor Warren Lee, an expert on diabetes in Asia, emphasized
Endocrinology
Diabetic cardiomyopathy, a condition characterized by interstitial fibrosis, is a prominent issue in patients with diabetes. According to researchers, hyperglycemia and hyperinsulinemia are common root causes of this pathology, which is often a result of type 2 diabetes mellitus. This condition has the highest incidence of cardiovascular morbidity and mortality.
Neurosciences
Tercica, Inc., a biopharmaceutical company focused on the development and commercialization of recombinant human insulin-like growth factor-1 (rhIGF-1) for the treatment of short stature, diabetes, and other endocrine system disorders, has initiated a phase 3b clinical study to investigate the use of rhIGF-1 as a therapy for children with short
Neurosciences
Researchers in Japan have found that the angiotensin-converting enzyme (ACE) inhibitor perindopril can protect against neurodegeneration in a mouse model of Parkinson disease. The study, led by R. Kurosaki, evaluated the effects of perindopril on the dopaminergic system in mice after treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The results
Endocrinology
A study from the United States has discovered that indinavir, an HIV protease inhibitor, increases fasting glucose levels and worsens hepatic insulin sensitivity in healthy HIV-uninfected men. After four weeks of treatment, researchers found that fasting glucose production and glycogenolysis were significantly increased, and indinavir blunted the ability of insulin
Endocrinology
Decision Resources, a leading research and advisory firm, has forecast that Eli Lilly's launch of ruboxistaurin in 2006 will revolutionize the diabetic neuropathy drug market from a focus on pain control to disease modification. According to the new Pharmacor study, "Diabetic Neuropathy," ruboxistaurin has the potential
Endocrinology
Cerner Corp., a leader in healthcare technology, has announced a 10-year commitment to provide every child in the United States with Type 1 diabetes a personal health record (PHR). This initiative has the potential to improve the lives of over 1.3 million people living with the disease. Cerner plans
Endocrinology
Cerner Corp., a leader in healthcare technology, has announced a 10-year commitment to provide every child in the United States with Type 1 diabetes a personal health record (PHR). This initiative has the potential to improve the lives of millions of children and their families, reducing healthcare costs and improving
Endocrinology
Collagen cross-linking has been identified as a key contributor to aortic wall matrix stiffness in rats with diabetes, highlighting a potential mechanism for the increased risk of cardiovascular disease in individuals with diabetes. Researchers from the United States conducted a study to investigate the relationship between collagen cross-linking and aortic
