Diseases

Genetic research

Joint Meta-Analysis Reveals Novel Loci and Shared Biology in Coronary Artery Disease and Aortic Aneurysms

Researchers have conducted a joint meta-analysis of genome-wide association studies (GWAS) to identify novel pleiotropic and heterogenous loci shared by coronary artery disease (CAD), abdominal aortic aneurysms (AAAs), and thoracic aortic aneurysms (TAAs). The study leveraged the shared genetic architecture of these cardiovascular traits to uncover common patterns of enriched