DNA sequencing

Genetic research

Unraveling the Mystery of Transcription Factors: New Insight into Sequence-Diverse DNA Recognition

Researchers from the Guangdong Academy of Agricultural Sciences have made a groundbreaking discovery regarding the molecular mechanism of transcription factors, specifically the transcription factor AflR. According to the study published in Nature Communications, the DNA-binding domain of AflR employs a structured zinc cluster motif and disordered terminal regions to achieve

DNA

Rare Legionella longbeachae Pneumonia Case Undetected by Conventional Testing Revealed through Microbial Cell-Free DNA Sequencing

Researchers at the Reno School of Medicine have reported a severe community-acquired pneumonia case caused by the rare soil-associated organism Legionella longbeachae. The patient, who had initial symptoms of severe pneumonia, required intubation and extracorporeal membrane oxygenation before microbial cell-free DNA sequencing identified L longbeachae. The exact cause of the