Gastroenterology
Scientists at the University of California-San Diego have described the regulated production of chemokine CCL28 in human colon epithelium. The study, published in the American Journal of Physiology - Gastrointestinal and Liver Physiology, found that CCL28 is constitutively expressed by epithelial cells at several mucosal sites and functions as a
Gastroenterology
Scientists from the United States have uncovered a crucial mechanism through which extracellular ATP promotes cell proliferation in human pulmonary artery smooth muscle cells. This finding sheds light on the complex interplay between extracellular ATP, cyclic AMP response element-binding protein (CREB), and transient receptor potential channels (TRPC) in the pulmonary
Gastroenterology
Researchers in the United States have discovered that a combination of PTEN gene therapy and caffeine can synergistically suppress cell growth and induce apoptosis in colorectal cancer cells. This treatment, which involves the overexpression of the tumor suppressor PTEN gene and the use of caffeine, has been shown to be
Gastroenterology
Researchers from the University of Texas, M.D. Anderson Cancer Center have found that a combination of adenovirus-mediated transfer of the PTEN gene (Ad-PTEN) and caffeine can produce a synergistic therapeutic effect in colorectal cancer cells. This combination resulted in cell growth suppression and apoptosis in colorectal cancer cells, but
