Gene expression

Genetic research

Tripartite Motif Proteins Play Crucial Roles in Innate Immunity Against Gram-Negative Bacteria in Teleost Fish

Researchers from Hohai University in Nanjing, People's Republic of China, have discovered that two tripartite motif (TRIM) proteins, designated ToTRIM16 and ToTRIM65, play significant roles in innate immunity against Gram-negative bacteria in teleost fish. The study found that these proteins regulate autophagy-related gene expression and provide novel insights