Cancer
A new study published in Frontiers in Nutrition has highlighted the potential of probiotic-derived postbiotics as a sustainable and effective alternative to live microbial therapy in cancer gene therapy. Research from the School of Biosciences and Technology in Vellore, India, has shown that postbiotics, bioactive metabolites produced by probiotics, possess
Cancer
Researchers from JSS College of Pharmacy have made significant strides in the development of microneedle-based delivery systems for targeted cancer therapy. These minimally invasive systems have the potential to overcome the limitations of conventional drug delivery methods, enabling direct delivery of chemotherapeutic agents to tumor sites and reducing systemic toxicity.
Cancer
Researchers at Hamadan University of Medical Sciences in Iran have made significant progress in developing a targeted therapy for melanoma, one of the most prevalent and deadly forms of skin cancer. The study focuses on the AS1411 aptamer, a protein that targets the overexpressed nucleolin protein in melanoma cells, allowing
Cancer
Research conducted by a team of scientists at Nantong University has yielded a promising breakthrough in cancer gene therapy, offering a novel approach to treating neuropathic pain. By leveraging lipid nanoparticles as a delivery system, the team demonstrated the effectiveness of targeting the dorsal root ganglion (DRG) to alleviate pain.
Genetic research
Researchers from NanoVation Therapeutics have made significant strides in the development of lipid nanoparticles for gene therapy, a technology that can potentially be used to treat most diseases. According to a recent study published in the journal Molecular Therapy - Methods & Clinical Development, lipid nanoparticle technology can be designed
Cancer
Researchers from the National University of Singapore have made a groundbreaking discovery in the field of cancer gene therapy. According to their study, a new therapeutic strategy using extracellular vesicles (EVs) can effectively inhibit KRAS mutants and activate the RIG-I pathway, leading to a robust anti-tumor immune response. This approach
Cancer
Research at the University of Sharjah has made significant advancements in the field of cancer gene therapy by utilizing pH-responsive nanocarriers. This innovative approach enables targeted drug delivery and controlled release, offering a promising solution to the limitations of conventional cancer treatments. The study highlights the importance of exploiting the
Cancer
Research at Galgotias University has shed light on the potential of cyclodextrins (CDs) in cancer gene therapy. The study highlights the utility of CDs in forming inclusion complexes, enhancing the solubility and bioavailability of poorly soluble drugs. The researchers, led by Shikha Yadav, have explored the role of CDs in
Cancer
Research conducted by the Central University of Rajasthan has highlighted the importance of polymer nanotherapeutics in cancer treatment. The study emphasizes the potential of polymers in improving the solubility, stability, and bioavailability of therapeutic agents, leading to enhanced efficacy in cancer treatment. The researchers also stressed the significance of polyhydroxypropyl
Cancer
Researchers from the Datta Meghe College of Pharmacy have identified fisetin-loaded nanoformulations as a potential target-oriented therapy for psoriasis. Despite conventional therapies being available, the researchers argue that better and target-oriented treatments are needed. Fisetin, a flavonoid with antioxidant, anti-inflammatory, and immunomodulatory properties, has shown therapeutic potential but its poor
Genetic research
A team of researchers from the Indian Institute of Technology (IIT) Gandhinagar has made a breakthrough in the field of gene therapy, using fluorescent polyamines to efficiently condense DNA and facilitate cellular uptake. According to the study published in the journal Small, the newly synthesized polyamines, including spermine and spermidine
Genetic research
New research published in Clinical Cancer Research suggests a potential breakthrough in gene therapy for treating pancreatic cancer. The study, conducted by a team of researchers from ImmuXell Biotech Ltd. in Shanghai, China, developed an adoptive T-cell therapy that targets the KRAS G12V mutation, a common mutation found in pancreatic
