Cancer research
A team of researchers from the University of Rochester has discovered the biological defenses that enable long-lived bats to resist cancer. The study, published in Nature Communications, has found that four common species of bats can live up to 35 years without developing cancer, equivalent to about 180 human years.
Genetic research
Research from the University of Oslo has shown that exposure to air pollution and an unhealthy built environment increases disease risk by impacting metabolic risk factors and inflammation. The study, funded by the Erasmus Medical Center, Erasmus University, and the European Union's Horizon 2020, found associations between fine
Genetic research
Immunotherapy has transformed the treatment of head and neck squamous cell carcinoma (HNSCC), but despite advances, challenges persist in maximizing its potential. The current landscape of immunotherapy in HNSCC, including key clinical trials, emerging biomarkers, and novel therapeutic strategies, is being explored to overcome these challenges. Recent studies have shown
Genetic research
Research has unveiled significant developments in cancer gene therapy, specifically in the treatment of lung cancer with brain metastases. A recent study conducted by researchers from the Department of Colorectal Surgery highlights the potential of nanotechnology in enhancing both diagnostic and therapeutic approaches. The study explores the use of nanomaterials
Cancer research
Researchers at Medical University of Warsaw have made significant progress in understanding cancer gene therapy, particularly in the treatment of glioblastoma, the most aggressive and common type of primary brain cancer. Current treatments result in only a 12- to 15-month mean overall survival, emphasizing the urgent need for more effective
Cancer research
A team of researchers from Oregon State University has made a significant discovery in the field of gene therapy. By incorporating 40 saponins into a model lipid nanoparticle (LNP) formulation, they found that certain saponins, such as quillaic acid and macranthoidin B, can increase the LNP transfection efficiency and endosomal
Genetic research
A recent review published in Frontiers in Oncology has highlighted the use of nanomaterials as a promising approach in conquering cancer drug resistance and tumor recurrence. Researchers from the University of Hyderabad have emphasized the importance of targeted therapies in eradicating cancer stem cells, which are resistant to conventional treatments
Cancer research
A team of researchers from Oak Ridge National Laboratory has developed a new method to identify carcinogenic gene combinations using genome data from cancer patients. The approach, published in the journal BMC Bioinformatics, leverages the intrinsic topology of gene-patient mutations to identify potentially carcinogenic combinations. According to the research, the
Cancer research
Research conducted at Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital has shed light on the relationship between ferroptosis-related genes and overall survival in liver hepatocellular cancer (LIHC) and stomach adenocarcinoma (STAD). The study found that ferroptosis inducer drugs can overcome resistance to cancer therapy caused by traditional chemicals.
Genetic research
Research conducted at Tongji University has led to a new study on cancer gene therapy, focusing on manganese-based STING-activating tumor immunotherapy. The study highlights the limitations of this approach due to T cell exhaustion, with mitochondrial dysfunction being a key contributing factor. Researchers employed liposomes as nano-reactors to facilitate the
Genetic research
Research at the Department of Hematology and Blood Banking has shown that nanoparticles, particularly nanotechnology, hold transformative potential in the treatment of hematological malignancies, such as leukemia, lymphoma, and multiple myeloma. Despite limitations in conventional therapies, nanomedicine offers more effective and specific therapies by enhancing drug delivery and reducing toxicity.
Genetic research
Recent studies have made significant strides in developing cancer gene therapy, particularly in the delivery of Bone Morphogenetic Proteins (BMPs) to glioma tumors. Researchers from the Department of Pharmacy have identified the potential of BMPs in differentiating glioma cells, inhibiting tumor growth, and managing glioma stem cells. However, the clinical
