Genetic research
Research conducted by the Indian Council of Agricultural Research (ICAR) Central Institute of Freshwater Aquaculture has shed light on the nutrient utilization capacity of striped murrel during larval development. The study investigated the expression patterns and activity levels of pancreatic a-amylase in striped murrel larvae, revealing significant increases in a-amylase
Genetic research
India's biomanufacturing sector stands at rank 3 in the Asia-Pacific region and rank 12 globally, with pharma exports expected to cross $30 billion this year. The country's bioeconomy has grown significantly, from $10 billion in 2014 to nearly $170 billion today, and is projected to reach
Genetic research
Investigators from the University of KwaZulu-Natal Westville have published a new study on the seasonal and spatial variability of water quality parameters, antibiotic-resistant bacteria (ARB), and antibiotic-resistance genes (ARGs) in four municipal wastewater treatment plants (WWTPs) in the Durban region of KwaZulu-Natal, South Africa. The research found significant effects of
Genetic research
A new study published in Chemistry - An Asian Journal presents a comprehensive review of non-viral gene delivery systems, highlighting their therapeutic potential and current challenges. According to the research, non-viral vectors such as lipid nanoparticles, cationic polymers, and inorganic nanoparticles offer advantages over viral vectors, including superior safety profiles,
Genetic research
Researchers at Sungkyunkwan University School of Medicine in South Korea have developed a novel therapeutic strategy for lung cancer brain metastases using genetically engineered mesenchymal stem cells. The study, published in Cancer Research Communications, demonstrates the effectiveness of using autologous Wharton's Jelly-derived mesenchymal stem cells (WJ-MSCs) as vehicles
Genetic research
Researchers at the Institute of Medicinal Biotechnology have made significant advancements in the field of cancer gene therapy, utilizing nanoparticles to deliver therapeutic agents directly to cancer cells. This innovative approach has shown promise in addressing genetic skin disorders and cancers, offering localized treatment with enhanced bioavailability and reduced systemic
Genes
Recent research has shed light on the genetic factors influencing the risk of ischemic stroke in an Iranian population. Epigenetic studies have identified specific genes and molecular alterations that are associated with the risk of ischemic stroke, and understanding these genetic factors can aid in stroke prevention. A case-control study
Genes
Researchers have made significant progress in understanding alternative polyadenylation (APA) and alternative splicing (AS), two essential post-transcriptional mechanisms that enhance transcriptome diversity and regulate gene expression. This study, published in Experimental & Molecular Medicine, provides a comprehensive overview of computational strategies for APA and AS detection and differential analysis. The
Genes
Research conducted at Dalian Ocean University has shed light on the heat shock protein 70 (HSP70) gene family in the Yesso scallop, revealing a complex phenomenon of dynamic alternative splicing under high temperature stress. The study found that 63 HSP70 family members were identified in the Yesso scallop genome, with
Genes
Researchers at the University of California have made significant progress in understanding the gene regulatory networks that control early heart formation. A time course of single-nucleus RNA sequencing and ATAC sequencing in wild-type and MEF2C-null embryos revealed a "posteriorized" cardiac gene signature and chromatin landscape in the absence
Genes
Research at Gansu Agricultural University has shed light on the role of NaCl in accelerating tomato fruit coloring. The study found that moderate salt stress (50 mM NaCl treatment) reduced chlorophyll content, increased carotenoid and lycopene content, and accelerated tomato color transition without decreasing yield. The study identified a novel
Genes
Scientists at the Siberian Branch of the Russian Academy of Sciences have conducted a comprehensive transcriptomic meta-analysis to understand the mechanisms of plant stress response under high light conditions. The study, published in the International Journal of Molecular Sciences, analyzed 21 experiments covering 58 high light conditions, resulting in 218,
