Genes
Recent research has shed light on the genetic factors influencing the risk of ischemic stroke in an Iranian population. Epigenetic studies have identified specific genes and molecular alterations that are associated with the risk of ischemic stroke, and understanding these genetic factors can aid in stroke prevention. A case-control study
Genes
Researchers at Shandong University conducted a study to investigate the characteristics of biofilm formation on petroleum-based polyethylene (PE) and bio-based polylactic acid (PLA) microplastics, as well as the structure of bacterial communities and the enrichment and transfer of related resistance genes in marine environments. The study examined the effects of
Genes
Researchers at the International Islamic University in Islamabad, Pakistan, have identified 27 chitinase genes in chickpeas and classified them into five classes based on phylogenetic analysis. According to the study, these chitinase genes play a crucial role in plant defense mechanisms, growth, symbiotic relationships, and stress resistance. The researchers found
Genes
Researchers from King Saud University conducted a seven-year study to investigate the prevalence and genetic basis of antibiotic resistance in methicillin-resistant Staphylococcus aureus (MRSA) isolates from sickle cell disease (SCD) patients in Riyadh, Saudi Arabia. The study found that 0.9% of SCD patients exhibited MRSA bloodstream infections, primarily affecting
Genes
Researchers from Anhui Medical University have conducted a study on the spatiotemporal distributions of microorganisms and antibiotic resistance genes (ARGs) in Chaohu Lake, revealing significant correlations between microbiota and ARGs in lake water and intestinal contents, but weaker associations in sediments. The study identified 53 types of pesticides and 25
Genes
Research conducted by investigators at the University of Malaya in Kuala Lumpur, Malaysia, has provided new insights into the microbial diversity and potential pathogens found in pigeon droppings. The study utilized shotgun metagenomic sequencing to analyze 273 fresh faecal samples collected from the Universiti Tunku Abdul Rahman Kampar campus in
Genes
Research on the effects of urban organic manure application on the microbial ecology of invasive species has revealed significant alterations in the gut bacterial community structure and increased antibiotic resistance gene (ARG) diversity in giant African snails. The study, conducted by a team of researchers from the Chinese Academy of
Genes
Researchers from the Government Medical College, Patiala, Punjab, India, have published a new study on the genotoxic effects of pesticide exposure on agricultural workers in the region. The study found significant associations between genotoxicity and polymorphisms in DNA repair genes, suggesting potential biomarkers for susceptibility to DNA damage. Key Takeaways:
Genes
Researchers from Cathay General Hospital in Taipei, Taiwan, have outlined the pivotal role of skin barrier dysfunction in inflammatory skin diseases such as atopic dermatitis and psoriasis. A comprehensive review of recent advances in the transcriptional and post-transcriptional regulation of key skin barrier-related genes, including FLG, LOR, CLDN1, AQP3, and
Genes
Researchers at the University of California, Los Angeles (UCLA), have made significant progress in developing a stem cell gene therapy for alpha thalassemia major, a severe and inherited blood disorder that affects the production of hemoglobin. Led by Dr. Donald Kohn, a renowned gene therapy pioneer, the team has successfully
Genes
Research conducted by the Marche Polytechnic University in Italy has raised concerns about the potential spread of carbapenem resistance genes (CRGs) in insect-based bioconversion systems. The study, published in the journal Genes, investigated the influence of different agri-food-based diets on the loads and CRG occurrence during the bioconversion process. The
Genes
A team of researchers at the Affiliated Hospital of Nantong University in Nantong, People's Republic of China, has designed a multifunctional poly(amidoamine) dendrimer-based gene delivery system to target activated hepatic stellate cells (aHSCs) and mitigate liver fibrosis. This innovative platform leverages clusterin (CLU) for Kupffer cell evasion,
