Genetic research
The use of whole-genome sequencing (WGS) in prenatal diagnosis has gained significant attention in recent years due to its potential in improving diagnostic rates for fetuses with abnormal development. According to a newly published study, WGS has shown promising results in prenatal diagnosis, with evidence indicating that it can improve
Genetic research
Researchers from Dankook University in South Korea have made a groundbreaking discovery in the field of animal science and technology. The team, led by Sumin Ryu and including Hyunok Doo and Eun Sol Kim, has successfully sequenced and analyzed the complete genome of Lactiplantibacillus plantarum strain GA_C_14. The
Genetic research
Research conducted by investigators at Benha University has shed light on the potential role of CASP5 in the immunopathogenesis of rheumatoid arthritis (RA). The study, published in the Egyptian Rheumatology and Rehabilitation journal, investigated the association between CASP5 gene expression and plasma levels with RA susceptibility and disease activity in
Genetic research
Researchers from Jeonbuk National University in Iksan, South Korea, have made significant strides in understanding the Gram-negative bacteria Vibrio parahaemolyticus, which causes Acute Hepatopancreatic Necrosis Disease (AHPND) in shrimp. This devastating disease has far-reaching implications for global shrimp aquaculture, affecting millions of dollars in revenue each year. By sequencing and
Genetic research
A recent study published in Discover Oncology aims to map the research landscape on circulating tumor DNA (ctDNA) for colorectal cancer. The study collected articles and reviews from the Web of Science Core Collection and Scopus databases, conducting bibliometric analysis and visualization using VOSviewer, CiteSpace, and R packages. The analysis
Genetic research
Recent research at China Agricultural University has shed light on the genetic basis of body weight traits in the Beijing You Chicken, a Chinese indigenous breed renowned for its high-quality meat and eggs. The study, supported by various funding agencies, utilized whole-genome sequencing and genome-wide association studies (GWAS) to identify
Genetic research
A new study has found that astronauts experience accelerated ageing, with cells losing their ability to make healthy new cells and becoming more prone to DNA damage. The University of California sent stem cells to the International Space Station to investigate the impact of low gravity, and the results were
Genetic research
Researchers from Peking University Cancer Hospital and Institute have made significant strides in the field of cancer gene therapy by exploring the potential of exosomes in gastric cancer immunotherapy. Gastric cancer, ranked fifth among the most prevalent cancers globally, has a dismal prognosis. Immunotherapy, particularly immune checkpoint inhibitors, has shown
Genetic research
Researchers at UMass Chan Medical School have made significant progress in treating GM2 gangliosidosis, a group of inherited disorders including Tay-Sachs and Sandhoff diseases, using a dual vector gene therapy. The study, published in Nature Medicine, involved nine participants in four cohorts who received injections of two harmless viral vectors
Genetic research
Researchers at Nankai University in Tianjin, People's Republic of China, have identified SUMOylation-related genes that define prognostic subtypes in stomach adenocarcinoma. According to their study, published in Frontiers in Immunology, these genes play a crucial role in tumor progression and immune infiltration. The researchers developed a SUMOylation Risk
Genetic research
A team of researchers from Xi'an Jiaotong University has made significant progress in the development and optimization of a biodiesel-methanol mechanism using a genetic algorithm. The research, conducted by Ying Wang and her team, aimed to create a more accurate and realistic model for predicting the behavior of
Genetic research
A new study published in the Journal of Controlled Release has reported a breakthrough in the field of immunotherapy, indicating that immune checkpoint inhibitors (ICIs) can be more effective when complemented with early assessment of immune remodeling. Researchers from Sun Yat-sen University in Zhuhai, People's Republic of China,
