Genetic research
Researchers at the National Institutes of Health (NIH) and the University of California, San Diego, have discovered a strong association between fine-particulate air pollution and increased genomic changes in lung cancer tumors among people who have never smoked. By analyzing the largest-ever whole-genome analysis of lung cancer in individuals who
Genetic research
Research from SickKids Research Institute and Genome Canada has highlighted the benefits and limitations of whole-blood RNA profiling in refining genetic diagnoses and uncovering novel disease mechanisms. A study published in npj Genomic Medicine assessed blood-derived RNA-seq in a pediatric cohort previously assessed by genome sequencing. The results showed that
Genetic research
Research conducted by the National Institute of Oceanography and Fisheries (NIOF) in Alexandria, Egypt, has made a significant discovery in the field of marine science. The study found that dietary supplementation with the seaweed polysaccharide (PS) extracted from red seaweed, Pterocladia capillacea, has a profound effect on the growth, feed
Genetic research
Researchers at the Gloucester Marine Genomics Institute have found that marine protected areas (MPAs) can help ensure the long-term conservation of natural resources, biodiversity, ecosystem services, and cultural values in the face of anthropogenic change. The study used a novel approach, incorporating environmental DNA (eDNA) to overcome the challenges of
Genetic research
Researchers at Yangzhou University in Yangzhou, People's Republic of China, have conducted a study to explore the effect of dietary betaine on hepatic lipid metabolism in laying hens. The study involved 48 laying hens, divided into two groups: a control group and a group fed a diet supplemented
Genetic research
Research at the University of Colorado has made significant progress in understanding the role of endothelial cell (EC) heterogeneity in thrombosis and haemostasis. According to a new report published in Research and Practice in Thrombosis and Haemostasis, ECs from different vascular types exhibit distinct gene expression patterns and functional responses
Genetic research
Researchers at Mansoura University in Egypt have made a significant discovery in the field of personalized medicine, shedding light on the impact of genetic variations on the response to chemotherapy in patients with chronic lymphocytic leukemia (CLL). The study, published in the journal Frontiers in Bioscience-Scholar, found that variations in
Genetic research
Research has shown that combining pre-treatment MRI-derived radiomic features with clinical data improves the accuracy of predicting biochemical recurrence-free survival (BCRFS) after prostate radiotherapy. This retrospective cohort analysis included patients with biopsy-proven prostate cancer who received radiotherapy between 2007 and 2013 at two cancer centers in the UK. The study
Genetic research
A study published in the journal PLANTS, PEOPLE, PLANET has shed light on the importance of conserving genetic resources in key crops like sugarcane, particularly in the face of climate change. Conducted by researchers from Guangxi University, the study analyzed the chloroplast genomes of wild sugarcane to assess genetic diversity
Genetic research
Despite advancements in cardiovascular care, healthcare disparities remain a significant challenge, exacerbated by fragmented healthcare systems, unequal access to healthcare, and biased data collection. Research suggests that precision medicine relies on accurate and valid omics and phenomics, which can be harnessed from electronic health records. However, the lack of standardized
Genetic research
A team of researchers from the Indian Institute of Technology (IIT) Gandhinagar has made a breakthrough in the field of gene therapy, using fluorescent polyamines to efficiently condense DNA and facilitate cellular uptake. According to the study published in the journal Small, the newly synthesized polyamines, including spermine and spermidine
Genetic research
Researchers from Fudan University in Shanghai, People's Republic of China, have shed new light on the complexities of salivary gland fibrosis, a prevalent condition associated with various pathological states. Through a comprehensive single-cell transcriptomic atlas, the study has identified significant heterogeneity among fibroblasts in fibrotic submandibular glands compared
