Adipose tissue
A study published in Frontiers in Endocrinology has revealed that the increased life expectancy of people living with HIV (PLWHIV), due to the effectiveness of antiretroviral therapy, has led to a higher incidence of metabolic disorders such as dyslipidemia, insulin resistance, and adipose tissue redistribution. Researchers at Hospital Civil de
Cloning
Recent research at Charite University Hospital and School of Medicine in Berlin, Germany, has highlighted the importance of studying tissues to gain further insights into HIV persistence and clonality. The study found that clones of infected cells are shared between anatomical sites, and that infected cells belonging to the same
Adipose tissue
A study published in Frontiers in Endocrinology has revealed that the increased life expectancy of people living with HIV (PLWHIV), due to the effectiveness of antiretroviral therapy, has led to a higher incidence of metabolic disorders such as dyslipidemia, insulin resistance, and adipose tissue redistribution. Researchers at Hospital Civil de
Cloning
Recent research at Charite University Hospital and School of Medicine in Berlin, Germany, has highlighted the importance of studying tissues to gain further insights into HIV persistence and clonality. The study found that clones of infected cells are shared between anatomical sites, and that infected cells belonging to the same
Biological products industry
Researchers at the University of California have conducted a retrospective cohort study to evaluate factors associated with discontinuation of long-acting injectable (LAI) cabotegravir/rilpivirine (CAB/RPV) and describe virologic outcomes in those that returned to oral antiretroviral therapy (ART). The study found that individuals with substance use demonstrated a higher
Highly active antiretroviral therapy
The South African Health Products Regulatory Authority (SAHPRA) has approved an HIV prevention jab that provides six months of protection at a time, paving the way for a limited public sector rollout in April 2026. The "game-changing" shot, which contains the antiretroviral drug lenacapavir, has been hailed as
Disclosure of information
A study published in Scientific Reports has highlighted the link between HIV status disclosure and mental health challenges in children and adolescents living with HIV in Eastern Uganda. The research, conducted by Busitema University investigators, found that children and adolescents living with HIV who had been disclosed of their HIV
Highly active antiretroviral therapy
A recent study published in the JAIDS Journal of Acquired Immune Deficiency Syndromes examined the outcomes of rapid restart of antiretroviral therapy (ART) among people with HIV who have relinked to care at a safety-net HIV clinic in San Francisco. The researchers used electronic medical record data to conduct a
Children
Researchers from the Harvard University T.H. Chan School of Public Health have reported on the long-term outcomes of children treated with broadly neutralizing antibodies (bNAbs) for HIV-1. In a study published in the Clinical Infectious Diseases journal, the team investigated the use of dual bNAbs as an alternative to
HIV
Recent research conducted at Imperial College London has made significant breakthroughs in the treatment of HIV/AIDS. The study assessed the effectiveness of the WHO-recommended first-line dolutegravir-based antiretroviral therapy (ART) in programmatic settings in low- and middle-income countries (LMICs). The research revealed that adults receiving this treatment achieved high viral
Antiretroviral agents
A new cluster-randomized stepped-wedge trial in South Africa has shown that community-based peer navigators can effectively mobilize demand for HIV prevention and care among young adults in rural areas. The study, conducted in collaboration with the Africa Health Research Institute, aimed to investigate whether a tailored approach to HIV prevention
Cancer
Research from Chongqing University Cancer Hospital in China has uncovered a crucial link between HIV reservoirs and the development of lymphoma in people living with HIV (PLWH). Despite advancements in antiretroviral therapy, PLWH remain at high risk of lymphoma, with HIV reservoirs playing a significant role in lymphomagenesis. The study&
