Cancer
Immunophotonics, a clinical-stage biotech company, has announced the completion of the INJECTABL-1 multicenter Phase 1b/2a clinical trial of its proprietary glycan polymer, IP-001, for advanced solid tumors. The trial, conducted in five countries, aimed to evaluate the systemic immune-mediated anti-cancer effects of IP-001 following tumor ablation. The company reports
Cancer
Scientists at UCLA have demonstrated a novel approach to treating cancer by combining genetically engineered T cells with stem cells, resulting in the production of cancer-fighting immune cells in humans. This groundbreaking study, published in Nature Communications, represents a new way to deliver immunotherapy, with the potential to offer longer-lasting
Cancer research
Researchers from the Faculty of Pharmaceutical Sciences have conducted a study on the direct costs and cost drivers of perioperative and adjuvant systemic treatments for stage I-II non-small cell lung cancer (NSCLC) in Jordan. The study used micro-costing methodology to analyze direct medical expenses, including drug acquisition, preparation, administration, pre/
Cancer research
Researchers at the University of Colorado Anschutz Medical Campus, Montefiore Einstein Comprehensive Cancer Center, and Utrecht University have found that common respiratory infections, including COVID-19 and influenza, can awaken dormant breast cancer cells in the lungs. This discovery was made by analyzing mouse models and two population studies, which showed
Cancer research
Researchers at the University of Colorado Anschutz Medical Campus, Montefiore Einstein Comprehensive Cancer Center, and Utrecht University have found that common respiratory infections, including COVID-19 and influenza, can awaken dormant breast cancer cells in the lungs. This discovery was made by analyzing mouse models and two population studies, which showed
Cancer research
Researchers have published new findings on the use of perioperative chemoimmunotherapy in patients with resectable stage II to IIIA non-small cell lung cancer (NSCLC). The study, which analyzed data from over 1,300 patients, found that those who received chemoimmunotherapy had improved clinical distant metastasis-free survival rates compared to those
Cancer research
Researchers at the University of Lodz in Poland have published a comprehensive review of the therapeutic potential of emerging PD-1/PD-L1-targeted antibodies in colorectal cancer. The study highlights the current treatment options, including pembrolizumab, nivolumab, and dostarlimab, and explores the challenges and complexities of combination strategies. The researchers aim to
Cancer
Researchers from Imam Mohammad Ibn Saud Islamic University in Riyadh, Saudi Arabia, have conducted a study that sheds light on the role of glyoxalase 1 (GLO-1) in various types of cancer cells. The study, published in Frontiers in Oncology, found that GLO-1 is a significant biomarker across multiple cancers that
Cancer research
The kidney cancer research community is crying out for continued support from congressional funding to ensure that patients with renal cell carcinoma (RCC) and other disease types receive cutting-edge treatments. Eric Jonasch, MD, emphasizes the importance of extending funding for the benefit of patients with RCC. The Kidney Cancer Research
Cancer
Researchers at the University of California San Diego are exploring the potential of a plant virus to fight cancer. The cowpea mosaic virus (CPMV) has been shown to be effective in preclinical studies and canine cancer patients, as it activates the immune system to recognize and attack cancer cells. The
Cancer research
New research at the University of Nebraska Medical Center has found that glycosylation, specifically tumor cell sialylation, regulates immune evasion and metastasis in non-small cell lung cancer. The study, funded by various organizations including the National Institutes of Health, identified a key role for the ST6GalNAc-I enzyme in sialylation of
Cancer research
Scientists at Northwestern University have made a significant discovery in the field of cancer therapy, specifically in the treatment of brain tumors. Their research reveals that immunotherapy, a revolutionary approach in cancer treatment, can effectively combat brain tumors by harnessing the power of B-cell immunity. According to the study, B
