Cancer
A recent study published in BMC Cancer has revealed that immunotherapy treatment in patients with COVID-19 does not increase the risk of 30-day mortality. The study, conducted by researchers at Western University, analyzed data from Ontario, Canada, and found that 22% of patients who received immunotherapy treatment within 120 days
Cancer research
Research from Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital shed light on the relationship between BIN1 expression and CD8+ T cell infiltration in non-small cell lung cancer (NSCLC). The study discovered that BIN1 expression is downregulated in NSCLC tumor tissues, associated with advanced disease progression and
Cancer research
Researchers from the Cancer Hospital in Beijing, People's Republic of China, have made a significant discovery in the field of lung cancer. By analyzing ferroptosis-related genes (FRGs) in small cell lung cancer (SCLC), they have identified three distinct subtypes: S1, S2, and S3. These subtypes have been linked
Cancer research
Research published in the Journal for ImmunoTherapy of Cancer has identified early predictive markers for primary refractory disease in patients with metastatic urothelial carcinoma (mUC) treated with atezolizumab, a programmed cell death ligand 1 (PD-L1) inhibitor. The study, conducted by researchers at AdventHealth Cancer Institute, aimed to identify patients who
Cancer
Personalized medicine has been gaining momentum in recent years, particularly in the treatment of locally advanced upper gastrointestinal (GI) adenocarcinomas. Despite aggressive treatment, these cancers continue to pose a major global health concern, with poor overall survival and high recurrence rates. Recent studies have highlighted the need for more effective
Cancer
Researchers at Cancer Research Division in Thiruvananthapuram, India have developed a safer and more efficient approach to gene therapy in cancer treatment. The study has generated high-titer lentiviral vectors that can be used to create CAR-T cells. CAR-T cells are a type of immunotherapy that can be used to treat
Cancer
A new study has made a significant advancement in immunotherapy for patients with ALK/EGFR wt resectable non-small cell lung cancer (NSCLC). Researchers from the IRCCS Regina Elena National Cancer Institute used a combination of deep molecular profiling, spatial transcriptomics, and serum proteomic profiling to achieve a complete pathologic response
Cancer research
A new study on cancer gene therapy highlights the significant growth of Asia's involvement in cancer immunotherapy research, driven by cutting-edge facilities, innovative technologies, and collaborative efforts. The study, published in the Journal for ImmunoTherapy of Cancer, examines the challenges and opportunities facing the region in advancing cancer
Cancer research
Fresh data on Oncology - Acute Myeloid Leukemia are presented in a new report from a team of researchers at the University of Florida. According to the research stated, "PurposeWhile CD33 directed immunotherapies have caught significant interest in recent years, the only approved antibody-drug conjugate targeting this antigen for
Cancer
Researchers at the Chinese Academy of Medical Sciences have made a significant breakthrough in cancer treatment by developing a novel formulation of paclitaxel that exhibits strong anti-tumor effects and safety in combination with immunotherapy. The study, published in Materials Today Bio, demonstrates the potential of self-assembled nanoparticles to enhance cancer
Cancer
Researchers at Air Force Medical University have made significant progress in the development of cancer nanovaccines, leveraging nanovehicles to enhance immune responses and create personalized vaccines. According to the study, cancer vaccines can stimulate the immune system to target and destroy cancer cells by recognizing antigens and adjuvants. The research
Cancer research
According to a recent study published in Frontiers in Oncology, researchers from Hebei Medical University have conducted a meta-analysis to evaluate the efficacy and safety of oxaliplatin-based chemotherapy as a first-line treatment in elderly patients with metastatic colorectal cancer (mCRC). The study found that oxaliplatin significantly improved tumor response rates
