Infection
The human gut microbiota plays a crucial role in overall health, and alterations to this delicate balance can have significant effects on our wellbeing. Research has long suggested that human herpesviruses (HHVs), which are ubiquitous in most populations by the eighth decade of life, may be linked to various neurodegenerative
Infection
Patients who received REBYOTA, a single-dose fecal microbiota transplant, for recurrent Clostridioides difficile infection (rCDI) exhibited a significant improvement in their health-related quality of life (HR-QOL) and achieved treatment success at an 8-week follow-up. According to two real-world studies presented at IDWeek 2025, 75% of patients who received REBYOTA achieved
Infection
Single-stage revision total knee arthroplasty (TKA) has been found to be an effective alternative to two-stage revision for treating periprosthetic joint infection (PJI) following TKA. Research comparing medical complications, hospital readmissions, and failure between one- and two-component single-stage revision TKA for PJI found that patients with one-component exchanges had increased
Infection
Researchers at the University of Glasgow have made significant findings in the evaluation of mosquito-borne diseases, specifically malaria. Their study highlights the importance of robust statistical tools in assessing the effectiveness of control measures, which often rely on experimental infections or field populations. A well-chosen generalized linear or mixed model
Infection
A nationwide study across 47 hospitals has revealed that many serious bloodstream infections acquired in Indian hospitals emerge from unknown sources, pointing to hidden risks beyond the well-known threat of intravenous tubes. The researchers tracked 7,092 non-central line (CL) bloodstream infections over seven years and found an overall rate
Infection
A study published in Scientific Reports has investigated the effectiveness of lung point-of-care ultrasound (POCUS) in distinguishing between bacterial and viral etiologies in children with lower respiratory tract infections (LRTIs). The research, conducted at Vittore Buzzi Children's Hospital in Milano, Italy, included 162 children admitted with suspected LRTI
COVID-19
Research conducted by Quentin J. Leclerc and colleagues at the MESuRS lab, Conservatoire national des Arts et Metiers in Paris, France, has shown that dedicating hospitals to infected patients only, with healthcare workers alternating between shifts, can significantly reduce the number of cumulative cases and peak incidence of nosocomial infections.
COVID-19
Research on Coronavirus - COVID-19 conducted at Technical University Munich has shed light on the complex dynamics of SARS-CoV-2 infection. The study, published in Frontiers in Nutrition, found that SARS-CoV-2 infection alters lipid metabolism, leading to a significantly impaired lipid profile in patients compared to healthy controls. The research also
Medical research
A new study on Coronavirus Disease 2019 (COVID-19) has shed light on the mechanisms underlying the milder symptoms and lower mortality rates observed in children compared to adults. The research, conducted before the introduction of mass COVID-19 vaccination, examined the association between serum levels of angiotensin-converting enzyme 2 (ACE2) and
COVID-19
A new study conducted by researchers at Laval University in Quebec, Canada, has found that the effectiveness of COVID-19 vaccines in preventing long COVID and COVID-19 itself declines over time. According to the study, which was published in the Clinical Infectious Diseases journal, the one- and two-dose vaccine effectiveness against
Medical research
Researchers at the National University of Singapore have successfully designed a series of antimicrobial peptide (AMP)-modified chemical vapor deposition (CVD) graphene coatings for biomedical devices, such as contact lenses. These coatings exhibit remarkable properties that make them suitable for biomedical applications. The study highlights the potential of these coatings
Medical research
Research published in the journal Vaccines has shed light on the immune response elicited by COVID-19 infection and vaccination. A team of researchers from Cellular Technology Ltd. (CTL) in Ohio, USA, conducted a comprehensive analysis of SARS-CoV-2 Spike (S-antigen)-reactive memory B cells (B[mem]) in previously immunologically naive subjects
