Cancer research
Researchers from the First Affiliated Hospital of Zhengzhou University have discovered that immunotherapy can be enhanced to treat metastatic lung cancer. The study, published in Cancer Immunology, Immunotherapy, found that tumor-associated macrophages (TAMs) contribute to immune suppression in lung cancer by limiting the activation of CD8 T cells and cytokine
Cancer research
Roche, a global leader in oncology, announced today that it will present more than 30 abstracts across 10 cancer types at the European Society for Medical Oncology (ESMO) Congress 2025, held in Berlin, Germany from October 17-21. The data showcase Roche's commitment to delivering transformative medicines for some
Cancer research
Researchers at the National Cancer Center of China have made a breakthrough in refining and personalizing the use of consolidation immunotherapy in patients with limited-stage small cell lung cancer (LS-SCLC). A study presented at the International Association for the Study of Lung Cancer 2025 World Conference on Lung Cancer (WCLC)
Cancer research
Research led by Stanford Medicine has revealed that small cell lung cancer cells that metastasize to the brain form functional connections with neurons, leading to increased tumor growth. This interaction is driven by the electrical pulses from the neurons, which promotes cancer cell growth. The study highlights the critical role
Cancer research
The Lung Cancer Research Foundation (LCRF) and Oncology Advocates United for Climate and Health -- International (OUCH-I) are partnering to fund projects that examine the impact of environmental pollution and climate change on lung cancer risk, diagnosis, treatment, and outcomes. The program, titled OUCH-International and LCRF Research Grant Program on
Cancer research
Researchers at Monash University Malaysia have made a significant breakthrough in the treatment of brain cancer, using antibody-conjugated polymer nanoparticles to target and destroy cancer cells. According to the study, brain cancer remains a significant global health challenge, affecting over a million individuals worldwide, and the blood-brain barrier (BBB) has
Cancer research
Researchers from Sichuan University have made a significant breakthrough in the treatment of lung cancer, specifically squamous non-small cell lung cancer (sqNSCLC). A new study has demonstrated the efficacy of combining stereotactic body radiotherapy (SBRT), low-dose radiation (LDRT), sintilimab, and chemotherapy to improve outcomes for patients with locally advanced or
Cancer research
Researchers from King Saud University, Riyadh, Saudi Arabia, have identified two FDA-approved compounds, Radotinib and Alectinib, as potential therapeutic agents for lung cancer. By employing computational approaches to repurpose these drugs, the study aimed to overcome the challenges associated with existing MEK inhibitors, such as on-target toxicities and drug resistance.
Cancer research
New research from West China Hospital of Sichuan University suggests that lung cancer and asthma may be linked through shared genetic mechanisms. The study, which utilized multi-cohort data integration and machine learning-based screening, identified three hub biomarkers (P2RY14, ANXA3, and SLIT2) that could serve as diagnostic tools for both diseases.
Cancer research
Scientists at Shanghai Jiao Tong University have made a significant breakthrough in lung cancer immunotherapy, developing an inhalable lipid nanoparticle system that enables simultaneous delivery of mRNA encoding anti-discoidin domain receptor 1 (DDR1) single-chain variable fragments and siRNA targeting PD-L1 into pulmonary cancer cells. This innovative approach has shown promising
Cancer research
Research from NIMS University in Jaipur, India, presents an AI-driven framework that utilizes deep learning and machine learning techniques to enhance lung cancer classification in chest Computed Tomography (CT) scans. The framework, which employs SqueezeNet a lightweight Convolutional Neural Network (CNN) for feature extraction, achieves a high accuracy of 92.
Cancer research
Research conducted at Fudan University has found that an anti-platelet factor 4 (PF4) antibody can inhibit the proliferation of lung cancer cells without TP53 mutation by inducing apoptosis and cell cycle arrest. The study, published in Clinical and Translational Discovery, used a co-culture system of platelets and lung cancer cells
