Lymphomas

Clinical trials

Long-term Clinical Outcomes With Tisagenlecleucel in High-risk Relapsed/refractory Follicular Lymphoma

A new study published in the Haematologica journal provides four-year follow-up results on the efficacy, safety, and pharmacokinetics of tisagenlecleucel treatment for patients with relapsed/refractory follicular lymphoma. The study, led by researchers from the University Teaching Hospital, demonstrates robust and durable responses with tisagenlecleucel and a favorable safety profile,

Clinical trials

Long-term Clinical Outcomes With Tisagenlecleucel in High-risk Relapsed/refractory Follicular Lymphoma

A new study published in the Haematologica journal provides four-year follow-up results on the efficacy, safety, and pharmacokinetics of tisagenlecleucel treatment for patients with relapsed/refractory follicular lymphoma. The study, led by researchers from the University Teaching Hospital, demonstrates robust and durable responses with tisagenlecleucel and a favorable safety profile,

Pediatrics

Genomic Profiling of Pediatric Cutaneous T-Cell Lymphomas Reveals Frequent Tyrosine Kinase Gene Fusions

Pediatric cutaneous T-cell lymphoproliferative disorders are a complex and poorly understood group of rare diseases, including mycosis fungoides, lymphomatoid papulosis, and primary cutaneous anaplastic large cell lymphoma. Recent research has shed light on the molecular pathogenesis of these disorders, with the identification of recurrent tyrosine kinase gene fusions. A study

Cancer

FDA Approves Label Updates for CAR T-Cell Therapies to Reduce Patient Monitoring Requirements and Remove REMS Programs

The US FDA has approved label updates for lisocabtagene maraleucel (liso-cel; Breyanzi) in large B-cell lymphoma (LBCL) and other lymphomas, and idecabtagene vicleucel (ide-cel; Abecma) in multiple myeloma, to reduce certain patient monitoring requirements and remove the risk evaluation and mitigation strategy (REMS) programs. According to Bristol Myers Squibb, the