Malaria

Infection

Sensitive Near Point-of-Care Detection of Malaria Offers Scalable Solution for Elimination in Africa

Researchers from Imperial College London have developed a near point-of-care, LAMP-based diagnostic platform for malaria diagnosis using capillary blood. This platform has shown high sensitivity and specificity in detecting Plasmodium falciparum infections, including asymptomatic and submicroscopic cases, in African endemic countries. The study's findings have significant implications for

Cornell University. College of Agriculture and Life Sciences

Malaria Parasites Optimize Transmission Investment by Sensing Multiple Within-Host Cues

A new study published in PLOS Biology reveals that malaria parasites can optimize their transmission investment by sensing two within-host cues. Researchers at Cornell University found that parasites that detect two cues - log-transformed infected and uninfected red blood cell abundance - can accurately track the progression of the infection,

Malaria

Emerging Resistance to Artemisinin-Based Combination Therapy Threatens Malaria Treatment Efficacy in Sub-Saharan Africa

A recent study published in Malaria Journal has highlighted the growing threat of emerging artemisinin partial resistance to the treatment of uncomplicated malaria in sub-Saharan Africa. For over two decades, Artemisinin-based combination therapy (ACT) has been the first-line treatment for uncomplicated malaria in the region. However, researchers from Strathmore University