Medical research

Charcot-Marie-Tooth disease

Disease Progression in Brazilian Children and Adolescents with Charcot-Marie-Tooth Disease

Brazilian pediatric and adolescent populations with Charcot-Marie-Tooth disease (CMT) experience significant disease progression within 2 years, with measurable deterioration observed as early as 1 year. The total score on the Charcot-Marie-Tooth Pediatric Scale (CMTPedS) increased by 4.5 points throughout 2 years, indicating disease progression. Financial supporters for this research

Knee replacement arthroplasty

Effectiveness of Preoperative Rehabilitation and Telerehabilitation in Total Knee Arthroplasty: A Meta-Analysis

Research findings published in Archives of Physical Medicine and Rehabilitation have shed light on the effectiveness of preoperative rehabilitation and telerehabilitation in total knee arthroplasty (TKA). A meta-analysis of randomized controlled trials revealed that preoperative rehabilitation yielded significant improvements in functional recovery and pain relief after TKA, particularly during the

Medical research

Inclusive Orchestral Music Therapy Shows Promise in Treating Neurodevelopmental Disorders

Research has shown that music-based interventions may engage neural networks to improve executive function, language, and socio-emotional skills in individuals with neurodevelopmental disorders. A new study proposes a clinically adapted orchestral framework, called the IncluSive Orchestral mUsic therapy accordiNg to the euterpe methoD (I-SOUND), to integrate individual music therapy, orchestral

Medical research

Inclusive Orchestral Music Therapy Shows Promise in Treating Neurodevelopmental Disorders

Research has shown that music-based interventions may engage neural networks to improve executive function, language, and socio-emotional skills in individuals with neurodevelopmental disorders. A new study proposes a clinically adapted orchestral framework, called the IncluSive Orchestral mUsic therapy accordiNg to the euterpe methoD (I-SOUND), to integrate individual music therapy, orchestral

Medical research

Molecular Interplay Between Oxidative and Endoplasmic Reticulum Stress in Multiple Sclerosis

Research into the debilitating neurological condition of multiple sclerosis (MS) has identified oxidative stress and endoplasmic reticulum (ER) stress as pivotal contributors to its pathology. A report from the University of Sherbrooke highlights the critical bidirectional relationship between these stress pathways, which amplify neuroinflammation, impair glial function, and drive neurodegeneration.