Medical research
A new study on Coronavirus Disease 2019 (COVID-19) has shed light on the mechanisms underlying the milder symptoms and lower mortality rates observed in children compared to adults. The research, conducted before the introduction of mass COVID-19 vaccination, examined the association between serum levels of angiotensin-converting enzyme 2 (ACE2) and
Medical research
Research published in the journal Vaccines has shed light on the immune response elicited by COVID-19 infection and vaccination. A team of researchers from Cellular Technology Ltd. (CTL) in Ohio, USA, conducted a comprehensive analysis of SARS-CoV-2 Spike (S-antigen)-reactive memory B cells (B[mem]) in previously immunologically naive subjects
Medical research
In a study published in the Journal of Doctoral Nursing Practice, researchers from the University of Nebraska Medical Center implemented a quality improvement project aimed at identifying college students who lack protection against vaccine-preventable infections, particularly human papillomavirus (HPV) and hepatitis B (HepB). The project, conducted in 2023, used an
Medical research
Scientists at the University Medical Center Mainz in Germany have developed a groundbreaking new approach to mRNA vaccine delivery, enhancing efficacy and innate immune activation. By incorporating adjuvants into lipid nanoparticles, researchers have achieved efficient delivery and immune enhancement, paving the way for improved vaccine development. Key Takeaways: * The study
Medical research
Researchers have investigated the incidence of respiratory viral infections in hematopoietic stem cell transplant (HSCT) recipients, revealing high mortality rates associated with these infections. The study, conducted at the All India Institute of Medical Sciences (AIIMS), followed 100 HSCT recipients for 18 months, observing 318 respiratory episodes, of which 61
Medical research
Researchers from Bellvitge University Hospital have analyzed Pseudomonas aeruginosa strains causing bloodstream infections in neutropenic cancer patients across five Spanish hospitals between 2006 and 2018. The study aimed to characterize PA strains and assess the association between microbiological features and clinical outcomes. The research found high genetic diversity among PA
Medical research
Growing concern over the transmission of zoonotic diseases, particularly avian influenza (HPAI H5N1), has been raised by recent evidence demonstrating the role of raw meat-based diets (RMBDs) and raw milk feeding in companion animals. This has led to widespread outbreaks in poultry, wild birds, and mammals, including dairy cattle and
Medical research
A recent study published in Mycopathologia has shed light on the high mortality rates associated with invasive pulmonary aspergillosis in hematological malignancy patients undergoing bronchoscopy. The research, conducted by a team of scientists at Uludag University in Bursa, Turkey, aimed to evaluate the risk factors associated with in-hospital mortality in
Medical research
A clinical trial has been registered in Australia to study the effectiveness of continuous glucose monitoring (CGM) and a culturally appropriate primary care pharmacist prescriber model of care in managing type 2 diabetes in Pacific adults. The trial, led by Prof Ben Wheeler, aims to investigate whether the use of
Medical research
Research from McMaster University, in collaboration with other institutions, has explored the recruitment challenges inherent in clinical research, particularly in older adults with depression. The study aimed to investigate the cost-effectiveness of various recruitment strategies for deep transcranial magnetic stimulation (dTMS) trials among this population. The analysis examined recruitment data
Medical research
The current landscape of AAV for the Hereditary Retinal Diseases is rapidly evolving with the emergence of novel gene therapies and innovative technologies aimed at treating genetic disorders causing progressive vision loss. Adeno-associated virus (AAV) vectors have been shown to be effective in delivering functional copies of defective genes directly
Medical research
A team of researchers from McGill University has published a study on the effectiveness of a decision support system (DSS) in improving glycemic control in adults with type 1 diabetes. According to the study, the DSS, which consists of a mobile application and a titration algorithm, provides weekly basal and
