Medical research
An observational cohort study of 7038 adult runners found that those with osteoarthritis were more likely to sustain running-related injuries (RRI) compared to healthy runners. The study, published in Physical Therapy In Sport, observed that 64.4% of runners with a disease and 56.7% of healthy runners sustained an
Mental health
Researchers from Universidad Central in Santa Clara, Cuba, have investigated the relationship between subjective cognitive concerns, psychological resilience, and quality of life in patients with multiple sclerosis (PwMS). The study involved 214 PwMS who were surveyed using the Multiple Sclerosis Quality of Life Inventory, the Multiple Sclerosis Neuropsychological Questionnaire (MSNQ)
B cells
Multiple sclerosis patient Emily Henders, 37, has become the first person in the UK to receive CAR T-cell therapy to treat the condition. Henders, a biology teacher, was diagnosed with multiple sclerosis on Christmas Eve in 2021 and has since experienced four debilitating relapses. Despite taking one of the most
Fatigue
Researchers have highlighted the prevalence of cognitive fatigue in multiple sclerosis patients, a symptom often misunderstood and undertreated. According to a study published in Frontiers in Neurology, cognitive fatigue is a core dysfunction affecting a person's ability to sustain mental effort over time, distinct from general fatigue. The
Medical research
Researchers at the Department of Physiotherapy have identified significant subcortical volume loss in patients with relapsing-remitting multiple sclerosis (RRMS), a chronic neurodegenerative disorder. According to a study published in the Irish Journal of Medical Science, the thalamus, nucleus caudatus, and nucleus lentiformis showed pronounced volume loss between the first and
Disabilities
Researchers have made significant findings on the impact of premorbid structural reserve on disability accumulation in multiple sclerosis (MS) patients. The study, conducted by a team of neuroscientists from S. Camillo-Forlanini Hospital in Rome, Italy, explored the influence of structural reserve, measured by intracranial volume (ICV) and spinal cervical canal
Medical research
Research into the debilitating neurological condition of multiple sclerosis (MS) has identified oxidative stress and endoplasmic reticulum (ER) stress as pivotal contributors to its pathology. A report from the University of Sherbrooke highlights the critical bidirectional relationship between these stress pathways, which amplify neuroinflammation, impair glial function, and drive neurodegeneration.
Multiple sclerosis
Researchers at Ohio State University College of Medicine have made a groundbreaking discovery in the treatment of progressive multiple sclerosis (MS). According to their study, published in the journal Frontiers in Immunology, senolytic therapy may provide a promising solution to the devastating neurodegenerative disease. Senolytic therapy targets and eliminates senescent
Medical research
A new report from the Mayo Clinic College of Medicine has shed light on the prevalence of critical demyelinating lesions in people with progressive multiple sclerosis (MS). The study, published in the Journal of Neurology, aimed to determine how frequently individual critical demyelinating lesions were found in an unselected consecutive
Multiple sclerosis
Researchers from the Neuroimmunology Group at Biogipuzkoa Health Research Institute in San Sebastian, Spain, have made significant strides in understanding the immunological changes that occur in multiple sclerosis (MS) patients as they age. The study, published in the journal Frontiers in Immunology, revealed distinct age-associated alterations in immune cell subsets
Multiple sclerosis
Researchers at the Southern University of Science and Technology (SUSTech) have developed a new model for multiple sclerosis, a chronic and debilitating neurological disease. According to a study published in Cell Death & Disease, the new model, based on repeated ablations of mature Tmem10+ oligodendrocytes, recapitulates key pathological features of
Multiple sclerosis
Researchers at the University of South Australia are studying the biology behind multiple sclerosis (MS) to predict genetic risk of developing the disease, potentially leading to early detection and prevention. Funded by an MS Australia Incubator Grant, the study will use a powerful new research method called 'recall by
