Nervous system diseases
Research by scientists at Women and Children's Hospital in Xiamen, Fujian, People's Republic of China has shed light on the crucial role of Med20 in regulating myelination in the peripheral nervous system. Myelin sheath is essential for the maintenance of neural system functions, and the mediator
Nervous system diseases
Research by scientists at Women and Children's Hospital in Xiamen, Fujian, People's Republic of China has shed light on the crucial role of Med20 in regulating myelination in the peripheral nervous system. Myelin sheath is essential for the maintenance of neural system functions, and the mediator
Biotechnology
Researchers at METiS TechBio have made a breakthrough in the development of a novel oral formulation for treating Pseudobulbar Affect (PBA), a neurological condition characterized by sudden, involuntary, and inappropriate episodes of laughing or crying. MTS-004, the company's internally developed small-molecule candidate, has successfully completed Phase III clinical
Medical research
A recent study by researchers from Okayama University has shed light on the optimal timing for surgery in patients with spinal cord injury without radiographic evidence of trauma (SCIWORET). The study found that early stage surgery for SCIWORET may yield favorable neurological improvements. The research involved retrospective analysis of patients
Bacterial meningitis
New research by Elbert John V. Layug and colleagues at the University of the Philippines Manila sheds light on the diagnosis of bacterial meningitis and ventriculitis in children. The team aimed to assess the utility of cerebrospinal fluid (CSF) procalcitonin (PCT) as a diagnostic marker in pediatric patients. The study
Medical research
Researchers from Rothschild Foundation Hospital, Paris, France, have conducted a comprehensive review of nonmotor symptoms (NMSs) in pediatric movement disorders, highlighting significant gaps in the evaluation of these symptoms. The study, published in the journal Neurology, emphasizes the importance of considering NMSs, such as tics, dystonia, and cerebral palsy, in
Migraine
A phase 3 trial, PRECLUDE, investigated the efficacy of onabotulinumtoxinA (onabotA) for preventing episodic migraine, a complex neurological disease characterized by recurring headache attacks. The study involved 775 patients aged 18-65 years, who were randomized to receive placebo, onabotA 155 U, or onabotA 195 U. The trial protocol included a
Medical research
A recent study published in the Neuromodulation journal has found that functional electrical stimulation (FEST) therapy can improve muscle strength in individuals with chronic spinal cord injuries (SCIs). Researchers from Simon Fraser University conducted a cohort study on 136 muscles treated with FEST from 17 participants with cervical SCI. The
Nervous system diseases
Researchers from the Second Affiliated Hospital of Fujian Medical University have discovered a potential therapeutic approach to mitigate spinal cord injury (SCI) using bone marrow stromal cells (BMSCs)-derived exosomal AKAP12. The study, published in the Journal of Molecular Medicine, found that exosomal AKAP12 inhibits neuronal ferroptosis by repressing TFRC-
Medical research
A recent study published in the journal Advanced Science has made a groundbreaking discovery in the treatment of spinal cord injuries. According to the research, a new approach using pharmacological microglial modulation has shown promise in remodelling the scar microenvironment to support reticulospinal circuit reconstruction after spinal cord injury. This
Migraine
A phase 3 trial, PRECLUDE, investigated the efficacy of onabotulinumtoxinA (onabotA) for preventing episodic migraine, a complex neurological disease characterized by recurring headache attacks. The study involved 775 patients aged 18-65 years, who were randomized to receive placebo, onabotA 155 U, or onabotA 195 U. The trial protocol included a
Nervous system diseases
Researchers from the Second Affiliated Hospital of Fujian Medical University have discovered a potential therapeutic approach to mitigate spinal cord injury (SCI) using bone marrow stromal cells (BMSCs)-derived exosomal AKAP12. The study, published in the Journal of Molecular Medicine, found that exosomal AKAP12 inhibits neuronal ferroptosis by repressing TFRC-
