Nervous system diseases
Research into neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis, has shed light on the critical role of microglia in the progression of these diseases. Microglial dysregulation, characterized by chronic neuroinflammation, exacerbates neuronal damage and impairs synaptic function. A recent study published in
Chiang Mai University
Research published in the journal Spinal Cord suggests that sympathetic skin response (SSR) induced by supraorbital nerve stimulation can be a reliable tool for evaluating autonomic functions in individuals with spinal cord injury (SCI). The study, conducted by researchers at Chiang Mai University in Thailand, assessed the test-retest reliability of
Migraine
A phase 3 trial, PRECLUDE, investigated the efficacy of onabotulinumtoxinA (onabotA) for preventing episodic migraine, a complex neurological disease characterized by recurring headache attacks. The study involved 775 patients aged 18-65 years, who were randomized to receive placebo, onabotA 155 U, or onabotA 195 U. The trial protocol included a
Nervous system diseases
Researchers from the Second Affiliated Hospital of Fujian Medical University have discovered a potential therapeutic approach to mitigate spinal cord injury (SCI) using bone marrow stromal cells (BMSCs)-derived exosomal AKAP12. The study, published in the Journal of Molecular Medicine, found that exosomal AKAP12 inhibits neuronal ferroptosis by repressing TFRC-
Medical research
A recent study published in the Neuromodulation journal has found that functional electrical stimulation (FEST) therapy can improve muscle strength in individuals with chronic spinal cord injuries (SCIs). Researchers from Simon Fraser University conducted a cohort study on 136 muscles treated with FEST from 17 participants with cervical SCI. The
Immunotherapy
Researchers from Hunan University in Changsha, People's Republic of China, have made a groundbreaking discovery in the treatment of spinal cord injuries. They have developed a new hydrogel that can modulate microglia/macrophage polarization, leading to significant improvements in function recovery after spinal cord injury. The study, published
Immunotherapy
Researchers from Hunan University in Changsha, People's Republic of China, have made a groundbreaking discovery in the treatment of spinal cord injuries. They have developed a new hydrogel that can modulate microglia/macrophage polarization, leading to significant improvements in function recovery after spinal cord injury. The study, published
Medical research
Researchers at Maastricht University in the Netherlands have reported new findings on the adverse effects associated with transcranial magnetic stimulation (TMS) for psychiatric and neurological disorders. According to the study, TMS, while generally well-tolerated, is not without risks, with common adverse effects including headaches, scalp discomfort, nausea, and dizziness. The
Nervous system diseases
Doctors and neurosurgeons are highlighting a growing concern that women's brains are disproportionately affected by various neurological disorders, often leading to delayed diagnosis and treatment. According to Dr. Jay Jagannathan, a neurosurgeon from Michigan, US, women are more likely to experience migraines, multiple sclerosis, autoimmune-related neuropathies, and silent
Medical errors
Study results on Nervous System Diseases and Conditions - Nerve Injury have been published from Songkhla, Thailand, by researchers at Prince of Songkla University. The study aimed to evaluate the risk of iatrogenic peroneal nerve injury in all-inside meniscal repair with a vertical stitch, comparing between 90 degrees and 120
Nervous system diseases
A pilot study involving 12 patients with mild dementia and 7 age-matched healthy controls has demonstrated the potential of an AI-based cognitive prosthesis in improving executive function and task performance. The study aimed to evaluate whether the AI-based system, which integrates artificial intelligence and computer vision to guide users through
Medical research
Research from Wuhan University, published in Aging and Disease, has revealed a bidirectional relationship between circadian rhythms and neurological diseases. According to the study, intrinsic biological clocks drive the circadian rhythm, which coordinates physiological and pathological processes in the body. This has significant implications for the treatment of neurological diseases,
