Neurology
The Boston Biomedical Research Institute (BBRI) has announced an agreement with Wyeth Pharmaceuticals to license its patented technology for immunotherapy to combat Alzheimer's disease. This collaboration builds on the work of senior scientist Vic Raso, whose research forms the basis for the patent applications. The deal aims to
Neurology
A recent study conducted in Germany reveals that genes linked to cholesterol metabolism do not correlate with the development of Alzheimer's disease (AD). Despite initial associations between high cholesterol levels and an increased risk of AD, the scientific community has been searching for the underlying mechanisms. Researchers at
Neurology
European Union scientists have called for a healthy diet as a means to prevent or postpone debilitating problems such as Alzheimer's disease, osteoporosis, and colon cancer. The number of Europeans over 80 is expected to double in the next two decades, making proper eating habits crucial. Researchers have
Neurology
Researchers at the Blanchette Rockefeller Neurosciences Institute have made significant progress in developing new treatments for Alzheimer's disease. The institute has patented two novel approaches, one using bryostatin, a cancer treatment drug, and the other combining methylxanthine and phenylalanine. Initial lab animal studies suggest that these treatments can
Neurology
Alzheimer disease, the leading cause of dementia in the elderly, has been a source of hope for researchers as they continue to explore the potential benefits of statin drugs. Recent studies have shown that statins, a class of widely prescribed cholesterol-lowering drugs, may play a significant role in preventing or
Neurology
Researchers have discovered genetic loci responsible for determining susceptibility to the lethal effects of amyloid precursor protein transgene overexpression, a condition that can lead to central nervous system disorders and premature death in mice. The study found that FVB/N mice are more susceptible to the lethal effects of APP
Neurology
Scientists have made a significant breakthrough in understanding the progression of Alzheimer's disease by characterizing thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice. This research has also investigated the effect of passive A-beta immunotherapy on the clearance of these plaques. The study, conducted by Thierry Bussiere and colleagues at
Neurology
Prana Biotechnology, a company focused on developing treatments for Alzheimer disease and other age-related degenerative disorders, has announced plans to initiate a phase II/III study in the late first quarter or second quarter of 2005 to examine the effect of PBT-1 on moderate to severe Alzheimer disease patients. The
Cardiology
Spanish researchers have found a significant correlation between the hardness of drinking water and the risk of cardiovascular and cerebrovascular diseases. A study of 538 municipalities in Comunidad Valenciana, Spain, from 1991-1998 discovered that the protective effects of calcium and magnesium in drinking water were associated with a lower risk
Cardiology
Scientists in the United States have discovered that T-wave changes can be linked to electroconvulsive therapy (ECT) in patients with coronary artery disease. The researchers, led by K.E. O'Brien, found that ECT can cause ST depression and arrhythmias in these patients, likely due to increased myocardial oxygen
Neurology
Researchers at the University of Debrecen in Hungary conducted a study to examine the effect of capsular neuronal elements on post-hip arthroplasty pain in osteoarthritis patients. The study involved 22 patients who underwent total hip replacement surgery and were monitored for a 1-year follow-up period. The results showed a significant
Neurology
Researchers have discovered a critical step in how insulin works to regulate glucose uptake in skeletal muscle, a process that is key to managing blood sugar levels in people with diabetes. According to a study published in the journal Diabetes, insulin rapidly recruits microvasculature in skeletal muscle, which facilitates the
