Neurology

Neurology

DNA Repair Mechanisms Compromised in Alzheimer's Disease?

Researchers have found that chronic oxidative stress, proposed to occur during Alzheimer's disease, may alter the expression or activity of DNA double-strand break repair or base excision repair proteins. The study, published in Neurobiology of Aging, discovered that Ku DNA binding activity was reduced in extracts of postmortem

Neurology

Breakthrough in Neurodegenerative Disease Research: Targacept's Groundbreaking Findings

Research conducted by Targacept and the Medical College of Georgia has made significant strides in understanding the mechanisms of cell death in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. The study, published in The Journal of Neuroscience, reveals that the enzyme SHP-1 plays a crucial