Pediatrics
Research conducted in Blantyre, Malawi, has shed light on the safety of higher doses of blood transfusion for children hospitalized with severe anaemia. The study, led by Imperial College, observed 52 Malawian children aged 2 months to 12 years who were hospitalised with uncomplicated severe anaemia. The children were randomly
Pediatrics
Researchers from Rutgers University Robert Wood Johnson Medical School have made new discoveries in the field of Transfusion Medicine - Blood Transfusion, shedding light on factors associated with survival in massive transfusion protocol (MTP) activation among pediatric trauma patients. A study evaluated the factors associated with survival in MTP activation
Pediatrics
New research from Montpellier University Hospital in France has shed light on the most effective ways to manage and treat hemophilia, a congenital bleeding disorder affecting millions worldwide. The study, conducted by pediatric hematology and oncology experts, highlights the importance of early and long-term prophylaxis in reducing bleeding incidents and
Pediatrics
Scientists at the Department of Pediatrics, Guangzhou Development District Hospital, have made significant breakthroughs in understanding the role of microRNA-3164 (miR-3164) in regulating neutrophil extracellular traps (NETs) and its potential as a therapeutic target for asthma treatment. According to their study, published in the European Journal of Medical Research, miR-3164
Pediatrics
Pediatric cutaneous T-cell lymphoproliferative disorders are a complex and poorly understood group of rare diseases, including mycosis fungoides, lymphomatoid papulosis, and primary cutaneous anaplastic large cell lymphoma. Recent research has shed light on the molecular pathogenesis of these disorders, with the identification of recurrent tyrosine kinase gene fusions. A study
Infection
A study published in Scientific Reports has investigated the effectiveness of lung point-of-care ultrasound (POCUS) in distinguishing between bacterial and viral etiologies in children with lower respiratory tract infections (LRTIs). The research, conducted at Vittore Buzzi Children's Hospital in Milano, Italy, included 162 children admitted with suspected LRTI
Asthma
A recent study highlights the potential of smart inhaler systems in transforming paediatric asthma care by addressing fundamental problems affecting asthma outcomes, including medication adherence, inhalation technique, and reliever overuse. The research outlines key categories of smart inhalers and summarises the current evidence surrounding their use in children. However, technical
Pediatrics
A significant study has been published, revealing a crucial biomarker for risk stratification and clinical decision-making in pediatric respiratory infections. Researchers from Zhejiang University School of Medicine have identified a threshold effect of white blood cell count on the risk of refractory Mycoplasma pneumoniae pneumonia (RMPP) in pediatric patients. The
Pediatrics
Current study results on pediatric acute lymphoblastic leukemia (ALL) have been published, focusing on the prognostic value of prednisone response. The study, conducted by investigators at the First Affiliated Hospital of Guangxi Medical University, analyzed clinical data from 2,979 pediatric patients primarily diagnosed with ALL. The results showed that
Pediatrics
Researchers from the First Hospital of Jilin University in Changchun, People's Republic of China, have presented a rare case of a previously healthy 4-year-old boy developing hemophagocytic lymphohistiocytosis (HLH) symptoms following rotavirus infection. The child initially presented with severe pneumonia and a suspected lung abscess but subsequently developed
Pediatrics
Researchers at Chang Gung University have conducted a study on the relationship between urine output and time to methotrexate clearance in pediatric leukemia patients receiving high-dose methotrexate therapy. The study found that patients with higher urine output showed significantly faster methotrexate clearance, lower incidence of delayed clearance, and shorter hospital
Pediatrics
A new study from the University of Edinburgh has described the performance of various pediatric risk scores in predicting mortality among children hospitalized with acute lower respiratory tract infections in Kenya. The research, which was funded by the Wellcome Trust, assessed the performance of six different risk scores, including the
