Precision medicine

Machine learning

Personalized Medicine Breakthrough: Predicting SLE Activity through Hierarchical Machine Learning

Researchers from Fondazione Policlinico Universitario Agostino Gemelli IRCCS have developed a hierarchical machine learning model to predict 12-month SLE activity in patients with systemic lupus erythematosus (SLE). This innovative approach considers patient demographics, laboratory, clinical features, treatments, and pathways, resulting in a reliable tool for predicting SLE activity. The model

Machine learning

Hybrid Model Outperforms Conventional Models in Predicting Adverse Prognostic Features in Prostate Cancer

Researchers at the Shanghai University of Traditional Chinese Medicine have made significant progress in developing a hybrid model that integrates clinical characteristics with radiomics features to predict adverse prognostic features in prostate cancer. The study aimed to develop MRI-based radiomics machine learning models for predicting adverse pathological prognostic features in

Machine learning

New Machine Learning Framework for Cancer Diagnosis Offers High Accuracy and Interpretable Results

A team of researchers at Xi'an Jiaotong-Liverpool University has developed a novel machine learning framework, called OncoTrace-TOO, to accurately classify the tissue-of-origin in cancer patients, facilitating clinical diagnosis and personalized treatment. The framework utilizes gene expression profiles and identifies pan-cancer discriminative molecular features to achieve high predictive accuracy.